X.Header.
1 FileVersion,2.0
2 SoftwareVersion,2.3.0.44
3 SystemType,Gen3
4 </Header>
5 <Sample_Attributes>
6 ID,01002
7 Owner,Administrator
8 Comments,
9 Date,20220128
10 GeneRLF,NS_IO_360_v1.0
11 SystemAPF,n6_vDV1
12 AssayType,Non Specific
13 </Sample_Attributes>
14 <Lane_Attributes>
15 ID,4
16 FovCount,194
17 FovCounted,194
18 ScannerID,1706P0203
19 StagePosition,1
20 BindingDensity,0.38
21 CartridgeID,30102613280522-01
22 CartridgeBarcode,30102613280522
23 </Lane_Attributes>
24 <Code_Summary>
25 CodeClass,Name,Accession,Count
26 Endogenous,CCNO,NM_021147.4,14
27 Endogenous,MYC,NM_002467.3,632
28 Endogenous,CD79A,NM_001783.3,10
29 Endogenous,FSTL3,NM_005860.2,45
30 Endogenous,VCAN,NM_001126336.2,1141
31 Endogenous,CX3CL1,NM_002996.3,59
32 Endogenous,ERBB2,NM_004448.2,315
33 Endogenous,FAM124B,NM_001122779.1,21
34 Endogenous,AKT1,NM_005163.2,1050
35 Endogenous,KDR,NM_002253.2,79
36 Endogenous,EGF,NM_001178130.2,78
37 Endogenous,MAGEA12,NM_001166386.1,125
38 Endogenous,IFNA1,NM_024013.1,65
39 Endogenous,TGFB3,NM_001329938.1,75
40 Endogenous,MFGE8,NM_001114614.1,528
41 Endogenous,CXCL2,NM_002089.1,87
42 Endogenous,CCND2,NM_001759.2,144
43 Endogenous,PDZK1IP1,NM_005764.3,27
44 Endogenous,JAG2,NM_002226.4,38
45 Endogenous,C5,NM_001317163.1,21
46 Endogenous,CD79B,NM_001039933.1,13
47 Endogenous,CXCR2,NM_001557.3,17
48 Endogenous,PSMB10,NM_002801.3,79
49 Endogenous,ZEB1,NM_001128128.2,138
50 Endogenous,ANLN,NM_018685.2,121
51 Endogenous,TAF3,NM_031923.3,19
52 Endogenous,CD276,NM_001024736.1,939
53 Endogenous,ICAM1,NM_000201.2,70
54 Endogenous,IL16,NM_004513.4,52
55 Endogenous,CXCL3,NM_002090.2,17
56 Endogenous,PRR5,NM_015366.3,48
57 Endogenous,CTSW,NM_001335.3,13
58 Endogenous,CXCR4,NM_001008540.1,298
59 Endogenous,IFNGR2,NM_005534.3,483
60 Endogenous,CDH11,NM_001797.2,725
61 Endogenous,COL6A3,NM_004369.3,1878
62 Endogenous,GZMK,NM_002104.2,17
63 Endogenous,IRF2,NM_002199.3,165
64 Endogenous,RPL7A,NM_000972.2,2589
65 Endogenous,GPR160,NM_014373.1,198
66 Endogenous,MICA,NM_000247.1,52
67 Endogenous,TAPBPL,NM_018009.4,88
68 Endogenous,CXCL14,NM_004887.4,167
69 Endogenous,CD14,NM_001174105.1,88
70 Endogenous,IL18,NM_001243211.1,65
71 Endogenous,CLEC14A,NM_175060.1,24
72 Endogenous,HMGB1,NM_002128.5,102
73 Endogenous,KIF2C,NM_006845.2,64
74 Endogenous,RNLS,NM_001031709.2,35
75 Endogenous,RPTOR,NM_001163034.1,126
76 Endogenous,CD68,NM_001251.2,109
77 Endogenous,CCL13,NM_005408.2,9
78 Endogenous,CYBB,NM_000397.3,169
79 Endogenous,PLA2G2A,NM_000300.2,16
80 Endogenous,FGF13,NM_001139498.1,22
81 Endogenous,CNTFR,NM_147164.2,15
82 Endogenous,CD244,NM_001166663.1,17
83 Endogenous,CSF2RB,NM_000395.2,17
84 Endogenous,MAP3K7,NM_003188.3,278
85 Endogenous,FASLG,NM_000639.2,16
86 Endogenous,CD209,NM_021155.2,13
87 Endogenous,IRF7,NM_004029.2,465
88 Endogenous,PTCD2,NM_001284403.1,117
89 Endogenous,PIK3R2,NM_005027.3,382
90 Endogenous,LILRA5,NM_181879.2,23
91 Endogenous,IL32,NM_004221.4,297
92 Endogenous,CCND3,NM_001136017.2,45
93 Endogenous,BIRC5,NM_001168.2,198
94 Endogenous,LGALS9,NM_002308.3,42
95 Endogenous,RASAL1,NM_001193520.1,39
96 Endogenous,PDCD1LG2,NM_025239.3,39
97 Endogenous,IL11,NM_000641.3,51
98 Endogenous,PRKX,NM_005044.4,19
99 Endogenous,SNCA,NM_001146055.1,16
100 Endogenous,ADGRE1,NM_001256252.1,16
101 Endogenous,PSMB9,NM_002800.4,115
102 Endogenous,RUNX3,NM_001031680.2,26
103 Endogenous,PGPEP1,NM_001300927.1,33
104 Endogenous,MELK,NM_014791.2,160
105 Endogenous,ISG15,NM_005101.3,1631
106 Endogenous,EIF2B4,NM_001034116.1,117
107 Endogenous,IRF9,NM_006084.4,548
108 Endogenous,IL1A,NM_000575.3,32
109 Endogenous,FCRL2,NM_001159488.1,13
110 Endogenous,EIF4EBP1,NM_004095.3,1412
111 Endogenous,LTBP1,NM_000627.3,160
112 Endogenous,CD40LG,NM_000074.2,9
113 Endogenous,HEY1,NM_001040708.1,166
114 Endogenous,HLA-DQA1,NM_002122.3,295
115 Endogenous,PRLR,NM_000949.5,601
116 Endogenous,TNFRSF11A,NM_001270949.1,40
117 Endogenous,AREG,NM_001657.3,57
118 Endogenous,BBC3,NM_014417.4,180
119 Endogenous,EDN1,NM_001955.2,36
120 Endogenous,PARP12,NM_022750.3,264
121 Endogenous,PIK3CG,NM_001282426.1,38
122 Endogenous,IL4,NM_172348.1,13
123 Endogenous,F2RL1,NM_005242.4,48
124 Endogenous,CXCL6,NM_002993.3,20
125 Endogenous,TNFSF18,NM_005092.3,17
126 Endogenous,JAK3,NM_000215.2,44
127 Endogenous,NKG7,NM_005601.3,33
128 Endogenous,TAPBP,NM_003190.4,533
129 Endogenous,MTOR,NM_004958.3,200
130 Endogenous,SELP,NM_003005.3,13
131 Endogenous,HLA-E,NM_005516.5,670
132 Endogenous,GOT1,NM_002079.2,265
133 Endogenous,SMAP1,NM_001044305.2,157
134 Endogenous,CDKN1A,NM_000389.2,430
135 Endogenous,CD45RA,NM_002838.4,8
136 Endogenous,HNF1A,NM_000545.6,12
137 Endogenous,TICAM1,NM_182919.3,36
138 Endogenous,C1QA,NM_015991.3,100
139 Endogenous,CD86,NM_001206924.1,25
140 Endogenous,ITGA4,NM_000885.5,108
141 Endogenous,ROR2,NM_001318204.1,129
142 Endogenous,WNT7B,NM_058238.2,97
143 Endogenous,FLT1,NM_002019.4,381
144 Endogenous,CTAG1B,NM_001327.2,58
145 Endogenous,CLEC7A,NM_197954.2,83
146 Endogenous,TNFRSF4,NM_003327.3,18
147 Endogenous,MS4A6A,NM_152852.2,27
148 Endogenous,ANGPT2,NM_001147.2,113
149 Endogenous,APH1B,NM_001145646.1,169
150 Endogenous,RORC,NM_001001523.1,56
151 Endogenous,NECTIN2,NM_001042724.1,286
152 Endogenous,DPP4,NM_001935.3,31
153 Endogenous,CCL2,NM_002982.3,789
154 Endogenous,NF1,NM_000267.3,168
155 Endogenous,S100A9,NM_002965.3,1519
156 Endogenous,NFKBIA,NM_020529.2,1304
157 Endogenous,BNIP3L,NM_001330491.1,267
158 Endogenous,CST2,NM_001322.2,24
159 Endogenous,APOL6,NM_030641.3,178
160 Endogenous,BRD4,NM_001330384.1,320
161 Endogenous,SLC16A1,NM_003051.3,264
162 Endogenous,THBD,NM_000361.2,35
163 Endogenous,TIGIT,NM_173799.2,15
164 Endogenous,VSIR,NM_022153.1,17
165 Endogenous,TRIM21,NM_003141.3,118
166 Endogenous,NBN,NM_002485.4,371
167 Endogenous,WNT4,NM_030761.4,15
168 Endogenous,CXCL8,NM_000584.3,54
169 Endogenous,FGF9,NM_002010.2,11
170 Endogenous,C5AR1,NM_001736.3,17
171 Endogenous,TNFRSF1B,NM_001066.2,25
172 Endogenous,HLA-DRB5,NM_002125.3,17
173 Endogenous,GLUL,NM_002065.6,1920
174 Endogenous,LY9,NM_001033667.2,7
175 Endogenous,TAP1,NM_000593.5,295
176 Endogenous,IFIH1,NM_022168.3,778
177 Endogenous,DEPTOR,NM_001283012.1,138
178 Endogenous,CSF1R,NM_005211.3,186
179 Endogenous,MARCO,NM_006770.3,21
180 Endogenous,NFIL3,NM_001289999.1,133
181 Endogenous,IKBKG,NM_001099856.4,46
182 Endogenous,CD58,NM_001144822.1,36
183 Endogenous,LOXL2,NM_002318.2,64
184 Endogenous,SPRY4,NM_030964.3,42
185 Endogenous,NFAM1,NM_145912.5,9
186 Endogenous,SYK,NM_003177.5,61
187 Endogenous,COMP,NM_000095.2,314
188 Endogenous,IFI6,NM_002038.3,24292
189 Endogenous,RASGRF1,NM_001145648.1,329
190 Endogenous,HDAC5,NM_001015053.1,101
191 Endogenous,BAMBI,NM_012342.2,43
192 Endogenous,MAGEC1,NM_005462.4,12
193 Endogenous,FYN,NM_002037.5,89
194 Endogenous,TNFSF4,NM_001297562.1,40
195 Endogenous,CD274,NM_014143.3,31
196 Endogenous,PRKACB,NM_182948.2,47
197 Endogenous,IFIT2,NM_001547.4,164
198 Endogenous,PPARG,NM_005037.5,31
199 Endogenous,PTEN,NM_000314.6,178
200 Endogenous,FOXP3,NM_014009.3,20
201 Endogenous,SREBF1,NM_001005291.1,870
202 Endogenous,CD36,NM_001001548.2,99
203 Endogenous,AXIN1,NM_181050.1,83
204 Endogenous,KLRK1,NM_007360.3,19
205 Endogenous,GBP1,NM_002053.2,108
206 Endogenous,CXCL11,NM_005409.4,175
207 Endogenous,CXCL10,NM_001565.3,770
208 Endogenous,RIPK1,NM_003804.3,157
209 Endogenous,REN,NM_000537.3,6
210 Endogenous,PRF1,NM_001083116.1,17
211 Endogenous,EIF2AK2,NM_001135652.2,997
212 Endogenous,LIF,NM_002309.4,43
213 Endogenous,BRD3,NM_007371.3,225
214 Endogenous,IGF2R,NM_000876.2,133
215 Endogenous,FPR1,NM_002029.3,26
216 Endogenous,DUSP5,NM_004419.3,1036
217 Endogenous,APC,NM_001127510.2,394
218 Endogenous,HDAC3,NM_003883.3,224
219 Endogenous,CES3,NM_001185176.1,55
220 Endogenous,OAS2,NM_016817.2,1380
221 Endogenous,HDAC11,NM_001330636.1,51
222 Endogenous,THBS1,NM_003246.2,1778
223 Endogenous,SLC11A1,NM_000578.3,41
224 Endogenous,MAGEA3/A6,NM_005362.3,470
225 Endogenous,ARID1A,NM_006015.4,316
226 Endogenous,CD48,NM_001778.3,26
227 Endogenous,GZMA,NM_006144.3,13
228 Endogenous,ICOSLG,NM_015259.4,130
229 Endogenous,PIK3R5,NM_014308.3,37
230 Endogenous,GZMM,NM_005317.2,13
231 Endogenous,WNT5A,NM_003392.3,109
232 Endogenous,TLR4,NR_024168.1,79
233 Endogenous,GZMB,NM_004131.4,8
234 Endogenous,PARP9,NM_001146103.1,445
235 Endogenous,LY96,NM_001195797.1,154
236 Endogenous,RAD50,NM_005732.3,612
237 Endogenous,MX1,NM_001144925.2,451
238 Endogenous,CENPF,NM_016343.3,126
239 Endogenous,SELL,NM_000655.4,9
240 Endogenous,TNFSF10,NM_003810.3,378
241 Endogenous,IL12RB2,NM_001319233.1,23
242 Endogenous,CXCL9,NM_002416.2,22
243 Endogenous,TRAT1,NM_016388.3,5
244 Endogenous,STC1,NM_003155.2,61
245 Endogenous,IL2RB,NM_000878.2,18
246 Endogenous,LILRB4,NM_001278426.3,44
247 Endogenous,SOX2,NM_003106.2,9
248 Endogenous,HCK,NM_001172129.1,55
249 Endogenous,WNT2B,NM_001291880.1,20
250 Endogenous,IL1B,NM_000576.2,19
251 Endogenous,TLR1,NM_003263.3,60
252 Endogenous,CCL22,NM_002990.3,15
253 Endogenous,ICAM2,NM_000873.3,19
254 Endogenous,MAP3K12,NM_006301.3,59
255 Endogenous,JAG1,NM_000214.2,119
256 Endogenous,CCL3/L1,NM_021006.5,122
257 Endogenous,SOCS1,NM_003745.1,39
258 Endogenous,BCL2,NM_000633.2,198
259 Endogenous,MAP3K8,NM_001244134.1,213
260 Endogenous,MMP1,NM_002421.2,47
261 Endogenous,CMKLR1,NM_004072.2,40
262 Endogenous,TNFRSF17,NM_001192.2,10
263 Endogenous,TLR8,NM_138636.4,21
264 Endogenous,TPM1,NM_000366.5,580
265 Endogenous,CXorf36,NM_024689.2,48
266 Endogenous,NLRP3,NM_001079821.2,16
267 Endogenous,DEFB134,NM_001302695.1,16
268 Endogenous,HLA-DQA2,NM_020056.4,25
269 Endogenous,CX3CR1,NM_001171171.1,11
270 Endogenous,APLNR,NM_005161.4,7
271 Endogenous,MXI1,NM_001008541.1,88
272 Endogenous,FZD9,NM_003508.2,16
273 Endogenous,COL4A5,NM_000495.4,101
274 Endogenous,FCAR,NM_133278.2,13
275 Endogenous,BRCA2,NM_000059.3,85
276 Endogenous,SFRP4,NM_003014.2,163
277 Endogenous,TLR3,NM_003265.2,89
278 Endogenous,IL2RG,NM_000206.1,21
279 Endogenous,CD84,NM_001184879.1,60
280 Endogenous,HLA-DPA1,NM_033554.2,330
281 Endogenous,RBL2,NM_001323611.1,427
282 Endogenous,CCL18,NM_002988.3,135
283 Endogenous,IRF3,NM_001197122.1,126
284 Endogenous,TNFRSF8,NM_001243.3,4
285 Endogenous,KIR3DL2,NM_006737.2,5
286 Endogenous,TNFSF13,NM_003808.3,55
287 Endogenous,CLECL1,NM_172004.3,18
288 Endogenous,TNFRSF10B,NM_003842.3,59
289 Endogenous,MAGEC2,NM_016249.3,16
290 Endogenous,CDKN2A,NM_000077.4,91
291 Endogenous,ADM,NM_001124.2,178
292 Endogenous,PNOC,NM_001284244.1,35
293 Endogenous,CD247,NM_198053.2,39
294 Endogenous,PTPRC,NM_080921.3,61
295 Endogenous,OAS3,NM_006187.3,756
296 Endogenous,LAG3,NM_002286.5,86
297 Endogenous,FOSL1,NM_005438.3,118
298 Endogenous,EOMES,NM_001278182.1,38
299 Endogenous,IL10RA,NM_001558.2,76
300 Endogenous,WDR76,NM_024908.3,70
301 Endogenous,GPC4,NM_001448.2,51
302 Endogenous,SLAMF7,NM_021181.3,35
303 Endogenous,RSAD2,NM_080657.4,1136
304 Endogenous,TLR5,NM_003268.5,88
305 Endogenous,VEGFA,NM_001171623.1,1871
306 Endogenous,COL5A1,NM_000093.4,710
307 Endogenous,CD3D,NM_000732.4,41
308 Endogenous,FBP1,NM_001127628.1,226
309 Endogenous,ERO1A,NM_014584.2,1094
310 Endogenous,CCL21,NM_002989.2,18
311 Endogenous,E2F3,NM_001243076.2,174
312 Endogenous,LDHA,NM_001135239.1,7634
313 Endogenous,MS4A1,NM_021950.3,32
314 Endogenous,CD69,NM_001781.2,45
315 Endogenous,SERPINB5,NM_002639.4,46
316 Endogenous,FAP,NM_004460.2,331
317 Endogenous,ITGA2,NM_002203.3,160
318 Endogenous,SIGLEC5,NM_003830.3,16
319 Endogenous,SIRPB2,NM_001134836.1,21
320 Endogenous,EPM2AIP1,NM_014805.3,333
321 Endogenous,FGF18,NM_003862.2,12
322 Endogenous,HRAS,NM_005343.3,134
323 Endogenous,CCND1,NM_053056.2,823
324 Endogenous,LAMB3,NM_000228.2,63
325 Endogenous,ID4,NM_001546.3,24
326 Endogenous,CCL4,NM_002984.2,53
327 Endogenous,GZMH,NM_033423.3,15
328 Endogenous,API5,NM_001142930.1,525
329 Endogenous,PTGER4,NM_000958.2,32
330 Endogenous,ITGB8,NM_002214.2,39
331 Endogenous,TNKS,NM_003747.2,120
332 Endogenous,B2M,NM_004048.2,8147
333 Endogenous,TP53,NM_000546.2,118
334 Endogenous,MAGEB2,NM_002364.4,16
335 Endogenous,LYZ,NM_000239.2,298
336 Endogenous,NCAM1,NM_000615.6,9
337 Endogenous,TCL1A,NM_001098725.1,6
338 Endogenous,HDC,NM_002112.3,7
339 Endogenous,CD27,NM_001242.4,15
340 Endogenous,SBNO2,NM_001100122.1,181
341 Endogenous,PECAM1,NM_000442.4,251
342 Endogenous,SERPINH1,NM_001207014.1,131
343 Endogenous,SPP1,NM_000582.2,3435
344 Endogenous,EGFR,NM_005228.3,57
345 Endogenous,CASP8,NM_001228.4,35
346 Endogenous,CCNA1,NM_001111045.1,15
347 Endogenous,TNFAIP3,NM_001270508.1,36
348 Endogenous,CDC25C,NM_001790.4,33
349 Endogenous,CXCR6,NM_006564.1,16
350 Endogenous,DLL1,NM_005618.3,13
351 Endogenous,OAS1,NM_001032409.1,1120
352 Endogenous,HLA-DQB1,NM_002123.3,59
353 Endogenous,ROBO4,NM_019055.5,26
354 Endogenous,NFKB1,NM_003998.3,242
355 Endogenous,IFI27,NM_005532.3,11191
356 Endogenous,HLA-DMB,NM_002118.3,104
357 Endogenous,CDKN1C,NM_000076.2,43
358 Endogenous,CEP55,NM_018131.3,70
359 Endogenous,ARG1,NM_000045.3,13
360 Endogenous,PLOD2,NM_182943.2,642
361 Endogenous,LAIR1,NM_001289023.2,36
362 Endogenous,SHC2,NM_012435.2,40
363 Endogenous,STAT3,NM_003150.3,997
364 Endogenous,CD45RO,NM_080921.3,122
365 Endogenous,CD2,NM_001767.3,105
366 Endogenous,IL7R,NM_002185.3,31
367 Endogenous,FLNB,NM_001164319.1,673
368 Endogenous,PSMB5,NM_001130725.1,528
369 Endogenous,SLC1A5,NM_001145144.1,195
370 Endogenous,RICTOR,NM_001285439.1,250
371 Endogenous,ZAP70,NM_001079.3,34
372 Endogenous,TNFAIP6,NM_007115.3,151
373 Endogenous,BTLA,NM_001085357.1,8
374 Endogenous,RELA,NM_021975.3,156
375 Endogenous,MMP7,NM_002423.3,184
376 Endogenous,TCF3,NM_003200.3,201
377 Endogenous,IRF8,NM_002163.2,40
378 Endogenous,NOS2,NM_000625.4,6
379 Endogenous,A2M,NM_000014.4,694
380 Endogenous,CCL20,NM_001130046.1,20
381 Endogenous,MKI67,NM_002417.2,308
382 Endogenous,IFNGR1,NM_000416.2,202
383 Endogenous,INHBA,NM_002192.2,161
384 Endogenous,WNT5B,NM_030775.2,35
385 Endogenous,CXCL5,NM_002994.4,21
386 Endogenous,SOX10,NM_006941.3,8
387 Endogenous,EGR1,NM_001964.2,127
388 Endogenous,STAT4,NM_001243835.1,23
389 Endogenous,IFIT3,NM_001031683.3,490
390 Endogenous,GMIP,NM_001288998.1,12
391 Endogenous,ARNT2,NM_014862.3,153
392 Endogenous,UBE2C,NM_007019.2,188
393 Endogenous,CHUK,NM_001278.4,222
394 Endogenous,GHR,NM_000163.2,64
395 Endogenous,TPI1,NM_000365.5,2927
396 Endogenous,HAVCR2,NM_032782.3,81
397 Endogenous,GOT2,NM_002080.3,505
398 Endogenous,PIK3CA,NM_006218.2,103
399 Endogenous,TNFSF9,NM_003811.3,7
400 Endogenous,IDO1,NM_002164.5,24
401 Endogenous,APOE,NM_000041.2,553
402 Endogenous,LILRB2,NM_001278405.1,27
403 Endogenous,PARP4,NM_006437.3,283
404 Endogenous,PFKM,NM_000289.5,133
405 Endogenous,THY1,NM_006288.3,305
406 Endogenous,SAMD9,NM_017654.3,497
407 Endogenous,TGFB1,NM_000660.4,420
408 Endogenous,CD8A,NM_001768.6,24
409 Endogenous,SELE,NM_000450.2,23
410 Endogenous,CDKN2B,NM_004936.3,77
411 Endogenous,CD5,NM_001346456.1,18
412 Endogenous,HLA-A,NM_002116.7,1921
413 Endogenous,FZD8,NM_031866.1,21
414 Endogenous,BCL2L1,NM_001191.3,231
415 Endogenous,TNFRSF9,NM_001561.5,22
416 Endogenous,XCL1/2,NM_002995.2,37
417 Endogenous,MAGEA4,NM_001011548.1,10
418 Endogenous,PMS2,NM_000535.6,249
419 Endogenous,KLRD1,NM_002262.3,18
420 Endogenous,NFATC2,NM_173091.2,73
421 Endogenous,VEGFB,NM_003377.3,154
422 Endogenous,CDC20,NM_001255.1,52
423 Endogenous,OTOA,NM_001161683.1,11
424 Endogenous,TPSAB1/B2,NM_003294.3,84
425 Endogenous,P4HA1,NM_000917.3,415
426 Endogenous,P2RY13,NM_023914.2,9
427 Endogenous,EXO1,NM_006027.3,37
428 Endogenous,CD70,NM_001252.3,6
429 Endogenous,DDB2,NM_000107.2,166
430 Endogenous,NDUFA4L2,NM_020142.3,26
431 Endogenous,IFITM1,NM_003641.3,3082
432 Endogenous,IFNAR1,NM_000629.2,220
433 Endogenous,TREM1,NM_001242589.2,44
434 Endogenous,CXCL13,NM_006419.2,66
435 Endogenous,TWIST2,NM_001271893.3,6
436 Endogenous,HLA-DRB1,NM_002124.3,572
437 Endogenous,FGFR1,NM_001174064.1,286
438 Endogenous,TBXAS1,NM_001061.4,40
439 Endogenous,NCR1,NM_001145457.2,5
440 Endogenous,SOX11,NM_003108.3,25
441 Endogenous,TLR2,NM_001318787.1,129
442 Endogenous,TWF1,NM_002822.4,541
443 Endogenous,CCL5,NM_002985.2,64
444 Endogenous,ITGAL,NM_002209.2,22
445 Endogenous,MYCT1,NM_025107.2,23
446 Endogenous,CD96,NM_005816.4,13
447 Endogenous,PROM1,NM_001145847.1,20
448 Endogenous,OASL,NM_003733.2,158
449 Endogenous,IFNG,NM_000619.2,11
450 Endogenous,BATF3,NM_018664.2,23
451 Endogenous,EZH2,NM_004456.4,107
452 Endogenous,IRF5,NM_002200.3,34
453 Endogenous,PCK2,NM_001018073.2,137
454 Endogenous,EPCAM,NM_002354.2,498
455 Endogenous,CD19,NM_001770.4,19
456 Endogenous,GBP4,NM_052941.4,93
457 Endogenous,MSH6,NM_000179.2,72
458 Endogenous,TNFRSF11B,NM_002546.3,30
459 Endogenous,NOTCH1,NM_017617.3,54
460 Endogenous,CASP9,XM_011542270.1,40
461 Endogenous,RAD51C,NM_058216.2,45
462 Endogenous,HLA-DMA,NM_006120.3,333
463 Endogenous,SFRP1,NM_003012.3,29
464 Endogenous,MAGEA1,NM_004988.4,23
465 Endogenous,ENTPD1,NM_001098175.1,107
466 Endogenous,ROCK1,NM_005406.2,94
467 Endogenous,FCGR2A,NM_021642.3,184
468 Endogenous,NGFR,NM_002507.3,23
469 Endogenous,ALDOC,NM_005165.2,419
470 Endogenous,CCNE1,NM_001238.1,59
471 Endogenous,ITGAX,NM_000887.4,115
472 Endogenous,BLM,NM_000057.3,60
473 Endogenous,MLANA,NM_005511.1,20
474 Endogenous,FCGR1A,NM_000566.3,49
475 Endogenous,CD47,NM_001777.3,925
476 Endogenous,CSF2,NM_000758.3,13
477 Endogenous,CDH5,NM_001795.3,31
478 Endogenous,SLC7A5,NM_003486.6,316
479 Endogenous,GIMAP4,NM_018326.2,103
480 Endogenous,HIF1A,NM_181054.2,705
481 Endogenous,CDK2,NM_001290230.1,188
482 Endogenous,PDCD1,NM_005018.1,12
483 Endogenous,ATF3,NM_001674.3,66
484 Endogenous,TIE1,NM_005424.4,40
485 Endogenous,CD44,NM_001001392.1,630
486 Endogenous,ALDOA,NM_000034.3,4299
487 Endogenous,FAS,NM_000043.3,35
488 Endogenous,MRE11,NM_001330347.1,156
489 Endogenous,IL10,NM_000572.2,14
490 Endogenous,BMP2,NM_001200.3,10
491 Endogenous,BAX,NM_004324.3,291
492 Endogenous,EIF5AL1,NM_001099692.1,5
493 Endogenous,KIT,NM_000222.2,16
494 Endogenous,CDK6,NM_001145306.1,27
495 Endogenous,SPIB,NM_003121.3,10
496 Endogenous,PFKFB3,NM_004566.3,36
497 Endogenous,CXCL12,NM_199168.3,18
498 Endogenous,CSF3,NM_000759.3,7
499 Endogenous,KIR2DL3,NM_015868.2,17
500 Endogenous,CD40,NM_001250.5,40
501 Endogenous,IRF1,NM_002198.2,223
502 Endogenous,MGMT,NM_002412.3,183
503 Endogenous,GLUD1,NM_005271.2,334
504 Endogenous,IFI35,NM_005533.4,240
505 Endogenous,PF4,NM_002619.3,14
506 Endogenous,GPSM3,NM_001276501.1,39
507 Endogenous,SLC2A1,NM_006516.2,72
508 Endogenous,IL2,NM_000586.2,15
509 Endogenous,SNAI1,NM_005985.3,60
510 Endogenous,CTNNB1,NM_001098209.1,1955
511 Endogenous,NOTCH2,NM_024408.3,351
512 Endogenous,NFKB2,NM_001077494.3,124
513 Endogenous,IL33,NM_033439.3,18
514 Endogenous,TREM2,NM_018965.3,64
515 Endogenous,LAMC2,NM_005562.2,43
516 Endogenous,AQP9,NM_001320635.1,45
517 Endogenous,PRKCA,NM_002737.2,17
518 Endogenous,TSLP,NM_033035.4,15
519 Endogenous,HLA-DOB,NM_002120.3,9
520 Endogenous,ANGPTL4,NM_001039667.2,93
521 Endogenous,TNFRSF25,NM_148970.1,43
522 Endogenous,MS4A4A,NM_001243266.1,84
523 Endogenous,CLEC5A,NM_013252.2,39
524 Endogenous,ITGAM,NM_000632.3,19
525 Endogenous,MMP9,NM_004994.2,57
526 Endogenous,CD7,NM_006137.6,14
527 Endogenous,VHL,NM_198156.1,70
528 Endogenous,OLFML2B,NM_015441.1,45
529 Endogenous,IL6,NM_000600.3,24
530 Endogenous,TNFRSF1A,NM_001065.2,330
531 Endogenous,DKK1,NM_012242.2,14
532 Endogenous,FANCA,NM_001018112.1,38
533 Endogenous,TNF,NM_000594.3,58
534 Endogenous,LTB,NM_002341.1,18
535 Endogenous,PPARGC1B,NM_001172699.1,25
536 Endogenous,RPS6KB1,NM_001272042.1,133
537 Endogenous,CD38,NM_001775.2,24
538 Endogenous,DTX3L,NM_138287.3,598
539 Endogenous,TMEM173,NM_198282.1,279
540 Endogenous,NEIL1,NM_024608.2,66
541 Endogenous,HELLS,NM_001289067.1,168
542 Endogenous,TGFBR1,NM_001130916.2,206
543 Endogenous,MB21D1,NM_138441.2,45
544 Endogenous,CCR2,NM_001123041.2,17
545 Endogenous,MSH2,NM_000251.1,227
546 Endogenous,RAD51,NM_133487.3,26
547 Endogenous,TNFRSF18,NM_148901.1,26
548 Endogenous,FCGR3A/B,NM_000570.4,325
549 Endogenous,STAT1,NM_007315.3,2167
550 Endogenous,CTSS,NM_004079.3,430
551 Endogenous,PDK1,NM_002610.3,435
552 Endogenous,ITGAV,NM_001144999.2,612
553 Endogenous,ANGPT1,NM_001199859.1,21
554 Endogenous,BCL6B,NM_181844.3,15
555 Endogenous,CDH2,NM_001792.3,48
556 Endogenous,CSF3R,NM_000760.3,166
557 Endogenous,RELB,NM_006509.3,82
558 Endogenous,CXCL16,NM_001100812.1,109
559 Endogenous,IL6R,NM_000565.3,27
560 Endogenous,PDGFA,NM_033023.4,35
561 Endogenous,PIK3R1,NM_001242466.1,119
562 Endogenous,HK1,NM_000188.2,499
563 Endogenous,AXL,NM_001699.4,65
564 Endogenous,HK2,NM_000189.4,658
565 Endogenous,PDGFRB,NM_002609.3,347
566 Endogenous,FADD,NM_003824.3,92
567 Endogenous,CD74,NM_001025159.2,2455
568 Endogenous,RIPK2,NM_003821.5,124
569 Endogenous,CD45RB,ENST00000367367.1,45
570 Endogenous,BAD,NM_004322.3,86
571 Endogenous,PKM,NM_001206796.2,5714
572 Endogenous,KLRB1,NM_002258.2,15
573 Endogenous,ADORA2A,NM_000675.5,128
574 Endogenous,IFIT1,NM_001270930.1,1506
575 Endogenous,UBE2T,NM_014176.1,46
576 Endogenous,RPL23,NM_000978.3,3210
577 Endogenous,ARG2,NM_001172.3,32
578 Endogenous,TGFBR2,NM_001024847.2,114
579 Endogenous,CRABP2,NM_001199723.1,2655
580 Endogenous,BLK,NM_001330465.1,18
581 Endogenous,CCL14,NM_032962.4,41
582 Endogenous,CCNB1,NM_031966.2,421
583 Endogenous,STAT2,NM_005419.2,998
584 Endogenous,IKBKB,NM_001190720.2,238
585 Endogenous,ZEB2,NM_001171653.1,214
586 Endogenous,LRRC32,NM_005512.2,85
587 Endogenous,IL22RA1,NM_021258.2,33
588 Endogenous,ELOB,NM_007108.2,42
589 Endogenous,ITGA1,NM_181501.1,70
590 Endogenous,IL24,NM_001185158.1,20
591 Endogenous,PVRIG,NM_024070.3,49
592 Endogenous,RB1,NM_000321.2,252
593 Endogenous,SRP54,NM_001146282.1,170
594 Endogenous,ICAM3,NM_002162.3,90
595 Endogenous,CCR5,NM_000579.3,49
596 Endogenous,CTLA4,NM_001037631.2,25
597 Endogenous,GLS,NM_014905.4,68
598 Endogenous,ITGAE,NM_002208.4,120
599 Endogenous,MET,NM_000245.2,110
600 Endogenous,WNT3A,NM_033131.3,18
601 Endogenous,TYMP,NM_001113755.2,752
602 Endogenous,IFI16,NM_001206567.1,207
603 Endogenous,PVR,NM_001135768.2,68
604 Endogenous,P4HA2,NM_001017973.1,157
605 Endogenous,BRIP1,NM_032043.2,71
606 Endogenous,ESR1,NM_000125.2,23
607 Endogenous,DAB2,NM_001244871.1,120
608 Endogenous,DUSP1,NM_004417.3,111
609 Endogenous,CD8B,NM_172213.2,30
610 Endogenous,ACVR1C,NM_145259.2,29
611 Endogenous,IL15,NM_000585.4,25
612 Endogenous,KIR3DL1,NM_001322168.1,19
613 Endogenous,CDH1,NM_004360.3,3142
614 Endogenous,HES1,NM_005524.2,267
615 Endogenous,IHH,NM_002181.2,18
616 Endogenous,CCL19,NM_006274.2,24
617 Endogenous,C2,NM_000063.5,107
618 Endogenous,TLR7,NM_016562.3,23
619 Endogenous,IL2RA,NM_000417.2,19
620 Endogenous,PRKAA2,NM_006252.3,27
621 Endogenous,COL11A2,NM_001163771.1,13
622 Endogenous,TNFRSF10D,NM_003840.4,22
623 Endogenous,SIGLEC8,NM_014442.2,13
624 Endogenous,PC,NM_000920.3,103
625 Endogenous,IL17A,NM_002190.2,24
626 Endogenous,GLI1,NM_005269.2,19
627 Endogenous,GNG4,NM_001098721.1,37
628 Endogenous,LDHB,NM_001174097.2,572
629 Endogenous,DTX4,NM_015177.1,78
630 Endogenous,CD3G,NM_000073.2,14
631 Endogenous,S100A8,NM_002964.4,2954
632 Endogenous,ZC3H12A,NM_025079.2,29
633 Endogenous,IER3,NM_003897.3,280
634 Endogenous,CD4,NM_000616.4,29
635 Endogenous,S100A12,NM_005621.1,21
636 Endogenous,CD6,NM_001254751.1,16
637 Endogenous,CD163,NM_203416.2,144
638 Endogenous,DUSP2,NM_004418.3,22
639 Endogenous,HERC6,NM_001165136.1,158
640 Endogenous,MRC1,NM_002438.2,23
641 Endogenous,DLL4,NM_019074.2,36
642 Endogenous,SAMSN1,NM_001256370.1,63
643 Endogenous,CD28,NM_001243077.1,19
644 Endogenous,TAP2,NM_018833.2,321
645 Endogenous,ICOS,NM_012092.3,6
646 Endogenous,TNFSF12,NM_003809.2,45
647 Endogenous,IFITM2,NM_006435.2,956
648 Endogenous,DNMT1,NM_001130823.2,319
649 Endogenous,TNFSF8,NM_001244.3,32
650 Endogenous,TGFB2,NM_001135599.3,48
651 Endogenous,TMEM140,NM_018295.3,64
652 Endogenous,COL11A1,NM_001854.3,514
653 Endogenous,GIMAP6,NR_024115.1,20
654 Endogenous,IRF4,NM_002460.1,33
655 Endogenous,BNIP3,NM_004052.3,445
656 Endogenous,FPR3,NM_002030.4,225
657 Endogenous,HLA-C,NM_002117.4,1786
658 Endogenous,VEGFC,NM_005429.4,135
659 Endogenous,SIGLEC1,NM_023068.3,58
660 Endogenous,BID,NM_001196.3,40
661 Endogenous,MAPK10,NM_001318067.1,62
662 Endogenous,FCN1,NM_002003.4,16
663 Endogenous,H2AFX,NM_002105.2,71
664 Endogenous,CBLC,NM_001130852.1,34
665 Endogenous,CASP3,NM_032991.2,224
666 Endogenous,PIAS4,NM_015897.2,200
667 Endogenous,HLA-DRA,NM_019111.3,1430
668 Endogenous,ULBP2,NM_025217.2,19
669 Endogenous,CASP1,NM_001223.4,71
670 Endogenous,MS4A2,NM_000139.3,18
671 Endogenous,HSD11B1,NM_181755.2,21
672 Endogenous,GAS1,NM_002048.2,47
673 Endogenous,FUT4,NM_002033.3,41
674 Endogenous,CSF1,NM_000757.5,59
675 Endogenous,FAM30A,NR_026800.2,23
676 Endogenous,ITPK1,NM_001142593.2,273
677 Endogenous,BCAT1,NM_005504.6,81
678 Endogenous,CD80,NM_005191.3,43
679 Endogenous,C1QB,NM_000491.3,302
680 Endogenous,RELN,NM_005045.3,18
681 Endogenous,ICAM5,NM_003259.3,16
682 Endogenous,MAML2,NM_032427.1,39
683 Endogenous,OLR1,NM_002543.3,107
684 Endogenous,NFKBIE,NM_004556.2,58
685 Endogenous,WNT11,XM_011545241.2,20
686 Endogenous,LILRA3,NM_001172654.2,28
687 Endogenous,TNFSF13B,NM_001145645.2,51
688 Endogenous,TDO2,NM_005651.3,102
689 Endogenous,MAP3K5,NM_005923.3,64
690 Endogenous,HLA-F,NM_001098479.1,303
691 Endogenous,CD3E,NM_000733.3,28
692 Endogenous,RRM2,NM_001034.1,714
693 Endogenous,C7,NM_000587.2,33
694 Endogenous,TNFRSF14,NM_003820.3,203
695 Endogenous,FCGRT,NM_004107.4,216
696 Endogenous,WNT2,NM_003391.2,41
697 Endogenous,MICB,NM_005931.3,40
698 Endogenous,HMGA1,NM_145902.2,253
699 Endogenous,IL21R,NM_021798.3,19
700 Endogenous,CD300A,NM_001256841.1,38
701 Endogenous,TWIST1,NM_000474.3,160
702 Endogenous,IL1RN,NM_000577.3,34
703 Endogenous,CXCL1,NM_001511.3,18
704 Endogenous,SFXN1,NM_001322977.1,662
705 Endogenous,GNLY,NM_012483.3,11
706 Endogenous,NID2,NM_007361.3,231
707 Endogenous,NECTIN1,NM_002855.4,180
708 Endogenous,SERPINA1,NM_001127702.1,164
709 Endogenous,PDGFB,NM_002608.2,45
710 Endogenous,HLA-B,NM_005514.6,4911
711 Endogenous,VCAM1,NM_001078.3,190
712 Endogenous,HLA-DPB1,NM_002121.5,383
713 Endogenous,HLA-DOA,NM_002119.3,29
714 Endogenous,GBP2,NM_004120.4,128
715 Endogenous,ATM,NM_000051.3,343
716 Endogenous,PSMB8,NM_004159.4,275
717 Endogenous,MLH1,NM_000249.2,173
718 Endogenous,PLA1A,NM_015900.2,23
719 Endogenous,NT5E,NM_002526.3,109
720 Endogenous,PALMD,NM_017734.4,23
721 Endogenous,UBA7,NM_003335.2,148
722 Endogenous,PIK3CD,NM_001350234.1,36
723 Endogenous,NOD2,NM_022162.1,36
724 Endogenous,CEACAM3,NM_001277163.2,33
725 Endogenous,RIPK3,NM_006871.3,43
726 Endogenous,IL1R2,NR_048564.1,16
727 Endogenous,JAK1,NM_002227.1,316
728 Endogenous,ENO1,NM_001428.3,5271
729 Endogenous,LILRA1,NM_001278318.1,27
730 Endogenous,BBS1,NM_024649.4,83
731 Endogenous,MYD88,NM_002468.3,214
732 Endogenous,CXCR3,NM_001142797.1,13
733 Endogenous,CD1C,NM_001765.2,9
734 Endogenous,TLR9,NM_017442.2,20
735 Endogenous,CCL7,NM_006273.3,67
736 Endogenous,CPA3,NM_001870.2,68
737 Endogenous,SH2D1A,NM_001114937.2,20
738 Endogenous,CCR4,NM_005508.4,33
739 Endogenous,HDAC4,NM_006037.3,46
740 Endogenous,POLD1,NM_001256849.1,44
741 Endogenous,PTPN11,NM_001330437.1,610
742 Endogenous,JAK2,NM_004972.2,152
743 Endogenous,WNT10A,NM_025216.2,17
744 Endogenous,ITGB2,NM_000211.3,166
745 Endogenous,TYMS,NM_001071.1,269
746 Endogenous,KAT2B,NM_003884.4,125
747 Endogenous,ITGA6,NM_001316306.1,65
748 Endogenous,TBX21,NM_013351.1,24
749 Endogenous,BRCA1,NM_007294.3,42
750 Endogenous,COL17A1,NM_000494.3,51
751 Endogenous,BIRC3,NM_001165.4,20
752 Endogenous,KRAS,NM_004985.3,151
753 Endogenous,IL11RA,NM_147162.1,39
754 Endogenous,SIRPA,NM_001040023.1,101
755 Endogenous,CEBPB,NM_005194.3,357
756 Endogenous,VTCN1,NM_001253849.1,755
757 Endogenous,SGK1,NM_005627.3,161
758 Endogenous,NLRC5,NM_032206.4,135
759 Endogenous,CCL8,NM_005623.2,271
760 Endogenous,TRAF1,NM_001190945.1,25
761 Endogenous,ADAM12,NM_003474.5,523
762 Endogenous,MMRN2,NM_024756.2,61
763 Endogenous,PTGS2,NM_000963.1,29
764 Endogenous,SMAD5,NM_005903.5,224
765 Endogenous,LCK,NM_005356.4,34
766 Endogenous,ITGB3,NM_000212.2,45
767 Endogenous,FCGR2B,NM_001002273.1,99
768 Endogenous,NRAS,NM_002524.4,294
769 Endogenous,IL34,NM_001172771.1,40
770 Endogenous,LAMA1,NM_005559.3,57
771 Endogenous,CLEC4E,NM_014358.3,34
772 Endogenous,IL18R1,NM_001282399.1,40
773 Endogenous,MFNG,NM_002405.3,98
774 Endogenous,TTC30A,NM_152275.3,124
775 Endogenous,TNFRSF10C,NM_003841.3,73
776 Positive,POS_C(8),ERCC_00002.1,3852
777 Positive,POS_A(128),ERCC_00117.1,36727
778 Positive,POS_F(0.125),ERCC_00034.1,75
779 Positive,POS_D(2),ERCC_00092.1,725
780 Positive,POS_B(32),ERCC_00112.1,14523
781 Positive,POS_E(0.5),ERCC_00035.1,150
782 Negative,NEG_C(0),ERCC_00019.1,27
783 Negative,NEG_D(0),ERCC_00076.1,8
784 Negative,NEG_E(0),ERCC_00098.1,24
785 Negative,NEG_A(0),ERCC_00096.1,17
786 Negative,NEG_H(0),ERCC_00154.1,12
787 Negative,NEG_G(0),ERCC_00144.1,14
788 Negative,NEG_F(0),ERCC_00126.1,39
789 Negative,NEG_B(0),ERCC_00041.1,20
790 Housekeeping,UBB,NM_018955.3,3440
791 Housekeeping,PUM1,NM_001020658.1,615
792 Housekeeping,TLK2,NM_006852.3,144
793 Housekeeping,DNAJC14,NM_032364.5,201
794 Housekeeping,SF3A1,NM_005877.4,315
795 Housekeeping,POLR2A,NM_000937.2,460
796 Housekeeping,SDHA,NM_004168.3,339
797 Housekeeping,STK11IP,NM_052902.2,103
798 Housekeeping,NRDE2,NM_017970.3,179
799 Housekeeping,TBP,NM_001172085.1,117
800 Housekeeping,OAZ1,NM_004152.2,2242
801 Housekeeping,TBC1D10B,NM_015527.3,92
802 Housekeeping,GUSB,NM_000181.1,146
803 Housekeeping,PSMC4,NM_006503.2,209
804 Housekeeping,TFRC,NM_003234.1,489
805 Housekeeping,ABCF1,NM_001090.2,170
806 Housekeeping,TMUB2,NM_177441.2,82
807 Housekeeping,MRPL19,NM_014763.3,232
808 Housekeeping,G6PD,NM_000402.4,92
809 Housekeeping,ERCC3,NM_000122.1,454
810 </Code_Summary>
811 <Messages>
812 </Messages>Gene expression analysis of combined treatment of metastatic breast cancer
Study description
This study looks at how a combination of pembrolizumab, exemestane, and leuprolide affects the immune environment in premenopausal women with advanced breast cancer. It tracks changes in immune-related gene expression before and after treatment in 15 patients.
Work method illustrated by a flowchart
Untidy –> Tidy data
- Each variable is saved in its own column.
- Each observation is saved in its own row.
- Each “type” of observation is stored in a single table.
code_class gene accesion_number pre_count_1 post_count_1
1 Endogenous CCNO NM_021147.4 14 14
2 Endogenous MYC NM_002467.3 632 427
3 Endogenous CD79A NM_001783.3 10 17
4 Endogenous FSTL3 NM_005860.2 45 59
5 Endogenous VCAN NM_001126336.2 1141 838
6 Endogenous CX3CL1 NM_002996.3 59 57
7 Endogenous ERBB2 NM_004448.2 315 807
8 Endogenous FAM124B NM_001122779.1 21 23
9 Endogenous AKT1 NM_005163.2 1050 1259
10 Endogenous KDR NM_002253.2 79 152
11 Endogenous EGF NM_001178130.2 78 8
12 Endogenous MAGEA12 NM_001166386.1 125 7
13 Endogenous IFNA1 NM_024013.1 65 27
14 Endogenous TGFB3 NM_001329938.1 75 130
15 Endogenous MFGE8 NM_001114614.1 528 494
16 Endogenous CXCL2 NM_002089.1 87 18
17 Endogenous CCND2 NM_001759.2 144 226
18 Endogenous PDZK1IP1 NM_005764.3 27 17
19 Endogenous JAG2 NM_002226.4 38 30
20 Endogenous C5 NM_001317163.1 21 74
21 Endogenous CD79B NM_001039933.1 13 11
22 Endogenous CXCR2 NM_001557.3 17 23
23 Endogenous PSMB10 NM_002801.3 79 77
24 Endogenous ZEB1 NM_001128128.2 138 219
25 Endogenous ANLN NM_018685.2 121 22
26 Endogenous TAF3 NM_031923.3 19 22
27 Endogenous CD276 NM_001024736.1 939 482
28 Endogenous ICAM1 NM_000201.2 70 29
29 Endogenous IL16 NM_004513.4 52 67
30 Endogenous CXCL3 NM_002090.2 17 10
31 Endogenous PRR5 NM_015366.3 48 36
32 Endogenous CTSW NM_001335.3 13 14
33 Endogenous CXCR4 NM_001008540.1 298 147
34 Endogenous IFNGR2 NM_005534.3 483 326
35 Endogenous CDH11 NM_001797.2 725 735
36 Endogenous COL6A3 NM_004369.3 1878 1155
37 Endogenous GZMK NM_002104.2 17 12
38 Endogenous IRF2 NM_002199.3 165 184
39 Endogenous RPL7A NM_000972.2 2589 4987
40 Endogenous GPR160 NM_014373.1 198 678
41 Endogenous MICA NM_000247.1 52 41
42 Endogenous TAPBPL NM_018009.4 88 132
43 Endogenous CXCL14 NM_004887.4 167 6855
44 Endogenous CD14 NM_001174105.1 88 213
45 Endogenous IL18 NM_001243211.1 65 34
46 Endogenous CLEC14A NM_175060.1 24 95
47 Endogenous HMGB1 NM_002128.5 102 140
48 Endogenous KIF2C NM_006845.2 64 23
49 Endogenous RNLS NM_001031709.2 35 69
50 Endogenous RPTOR NM_001163034.1 126 99
51 Endogenous CD68 NM_001251.2 109 66
52 Endogenous CCL13 NM_005408.2 9 16
53 Endogenous CYBB NM_000397.3 169 243
54 Endogenous PLA2G2A NM_000300.2 16 31
55 Endogenous FGF13 NM_001139498.1 22 46
56 Endogenous CNTFR NM_147164.2 15 22
57 Endogenous CD244 NM_001166663.1 17 11
58 Endogenous CSF2RB NM_000395.2 17 24
59 Endogenous MAP3K7 NM_003188.3 278 389
60 Endogenous FASLG NM_000639.2 16 14
61 Endogenous CD209 NM_021155.2 13 32
62 Endogenous IRF7 NM_004029.2 465 177
63 Endogenous PTCD2 NM_001284403.1 117 174
64 Endogenous PIK3R2 NM_005027.3 382 256
65 Endogenous LILRA5 NM_181879.2 23 17
66 Endogenous IL32 NM_004221.4 297 165
67 Endogenous CCND3 NM_001136017.2 45 83
68 Endogenous BIRC5 NM_001168.2 198 24
69 Endogenous LGALS9 NM_002308.3 42 41
70 Endogenous RASAL1 NM_001193520.1 39 28
71 Endogenous PDCD1LG2 NM_025239.3 39 33
72 Endogenous IL11 NM_000641.3 51 18
73 Endogenous PRKX NM_005044.4 19 13
74 Endogenous SNCA NM_001146055.1 16 19
75 Endogenous ADGRE1 NM_001256252.1 16 9
76 Endogenous PSMB9 NM_002800.4 115 73
77 Endogenous RUNX3 NM_001031680.2 26 38
78 Endogenous PGPEP1 NM_001300927.1 33 60
79 Endogenous MELK NM_014791.2 160 53
80 Endogenous ISG15 NM_005101.3 1631 150
81 Endogenous EIF2B4 NM_001034116.1 117 104
82 Endogenous IRF9 NM_006084.4 548 421
83 Endogenous IL1A NM_000575.3 32 22
84 Endogenous FCRL2 NM_001159488.1 13 20
85 Endogenous EIF4EBP1 NM_004095.3 1412 128
86 Endogenous LTBP1 NM_000627.3 160 99
87 Endogenous CD40LG NM_000074.2 9 13
88 Endogenous HEY1 NM_001040708.1 166 367
89 Endogenous HLA-DQA1 NM_002122.3 295 15
90 Endogenous PRLR NM_000949.5 601 1434
91 Endogenous TNFRSF11A NM_001270949.1 40 20
92 Endogenous AREG NM_001657.3 57 46
93 Endogenous BBC3 NM_014417.4 180 210
94 Endogenous EDN1 NM_001955.2 36 23
95 Endogenous PARP12 NM_022750.3 264 130
96 Endogenous PIK3CG NM_001282426.1 38 53
97 Endogenous IL4 NM_172348.1 13 11
98 Endogenous F2RL1 NM_005242.4 48 19
99 Endogenous CXCL6 NM_002993.3 20 17
100 Endogenous TNFSF18 NM_005092.3 17 14
101 Endogenous JAK3 NM_000215.2 44 23
102 Endogenous NKG7 NM_005601.3 33 58
103 Endogenous TAPBP NM_003190.4 533 546
104 Endogenous MTOR NM_004958.3 200 183
105 Endogenous SELP NM_003005.3 13 22
106 Endogenous HLA-E NM_005516.5 670 644
107 Endogenous GOT1 NM_002079.2 265 228
108 Endogenous SMAP1 NM_001044305.2 157 219
109 Endogenous CDKN1A NM_000389.2 430 216
110 Endogenous CD45RA NM_002838.4 8 20
111 Endogenous HNF1A NM_000545.6 12 21
112 Endogenous TICAM1 NM_182919.3 36 31
113 Endogenous C1QA NM_015991.3 100 79
114 Endogenous CD86 NM_001206924.1 25 19
115 Endogenous ITGA4 NM_000885.5 108 76
116 Endogenous ROR2 NM_001318204.1 129 62
117 Endogenous WNT7B NM_058238.2 97 12
118 Endogenous FLT1 NM_002019.4 381 429
119 Endogenous CTAG1B NM_001327.2 58 13
120 Endogenous CLEC7A NM_197954.2 83 96
121 Endogenous TNFRSF4 NM_003327.3 18 22
122 Endogenous MS4A6A NM_152852.2 27 44
123 Endogenous ANGPT2 NM_001147.2 113 79
124 Endogenous APH1B NM_001145646.1 169 234
125 Endogenous RORC NM_001001523.1 56 67
126 Endogenous NECTIN2 NM_001042724.1 286 578
127 Endogenous DPP4 NM_001935.3 31 23
128 Endogenous CCL2 NM_002982.3 789 150
129 Endogenous NF1 NM_000267.3 168 178
130 Endogenous S100A9 NM_002965.3 1519 32
131 Endogenous NFKBIA NM_020529.2 1304 903
132 Endogenous BNIP3L NM_001330491.1 267 102
133 Endogenous CST2 NM_001322.2 24 44
134 Endogenous APOL6 NM_030641.3 178 140
135 Endogenous BRD4 NM_001330384.1 320 191
136 Endogenous SLC16A1 NM_003051.3 264 72
137 Endogenous THBD NM_000361.2 35 56
138 Endogenous TIGIT NM_173799.2 15 14
139 Endogenous VSIR NM_022153.1 17 26
140 Endogenous TRIM21 NM_003141.3 118 62
141 Endogenous NBN NM_002485.4 371 151
142 Endogenous WNT4 NM_030761.4 15 33
143 Endogenous CXCL8 NM_000584.3 54 12
144 Endogenous FGF9 NM_002010.2 11 14
145 Endogenous C5AR1 NM_001736.3 17 17
146 Endogenous TNFRSF1B NM_001066.2 25 40
147 Endogenous HLA-DRB5 NM_002125.3 17 1866
148 Endogenous GLUL NM_002065.6 1920 6088
149 Endogenous LY9 NM_001033667.2 7 16
150 Endogenous TAP1 NM_000593.5 295 124
151 Endogenous IFIH1 NM_022168.3 778 225
152 Endogenous DEPTOR NM_001283012.1 138 160
153 Endogenous CSF1R NM_005211.3 186 275
154 Endogenous MARCO NM_006770.3 21 17
155 Endogenous NFIL3 NM_001289999.1 133 83
156 Endogenous IKBKG NM_001099856.4 46 65
157 Endogenous CD58 NM_001144822.1 36 39
158 Endogenous LOXL2 NM_002318.2 64 41
159 Endogenous SPRY4 NM_030964.3 42 81
160 Endogenous NFAM1 NM_145912.5 9 13
161 Endogenous SYK NM_003177.5 61 53
162 Endogenous COMP NM_000095.2 314 247
163 Endogenous IFI6 NM_002038.3 24292 1707
164 Endogenous RASGRF1 NM_001145648.1 329 15
165 Endogenous HDAC5 NM_001015053.1 101 216
166 Endogenous BAMBI NM_012342.2 43 220
167 Endogenous MAGEC1 NM_005462.4 12 18
168 Endogenous FYN NM_002037.5 89 150
169 Endogenous TNFSF4 NM_001297562.1 40 26
170 Endogenous CD274 NM_014143.3 31 15
171 Endogenous PRKACB NM_182948.2 47 81
172 Endogenous IFIT2 NM_001547.4 164 31
173 Endogenous PPARG NM_005037.5 31 85
174 Endogenous PTEN NM_000314.6 178 244
175 Endogenous FOXP3 NM_014009.3 20 25
176 Endogenous SREBF1 NM_001005291.1 870 10672
177 Endogenous CD36 NM_001001548.2 99 494
178 Endogenous AXIN1 NM_181050.1 83 74
179 Endogenous KLRK1 NM_007360.3 19 19
180 Endogenous GBP1 NM_002053.2 108 22
181 Endogenous CXCL11 NM_005409.4 175 16
182 Endogenous CXCL10 NM_001565.3 770 51
183 Endogenous RIPK1 NM_003804.3 157 346
184 Endogenous REN NM_000537.3 6 13
185 Endogenous PRF1 NM_001083116.1 17 17
186 Endogenous EIF2AK2 NM_001135652.2 997 545
187 Endogenous LIF NM_002309.4 43 21
188 Endogenous BRD3 NM_007371.3 225 295
189 Endogenous IGF2R NM_000876.2 133 315
190 Endogenous FPR1 NM_002029.3 26 34
191 Endogenous DUSP5 NM_004419.3 1036 402
192 Endogenous APC NM_001127510.2 394 595
193 Endogenous HDAC3 NM_003883.3 224 400
194 Endogenous CES3 NM_001185176.1 55 13
195 Endogenous OAS2 NM_016817.2 1380 173
196 Endogenous HDAC11 NM_001330636.1 51 86
197 Endogenous THBS1 NM_003246.2 1778 1329
198 Endogenous SLC11A1 NM_000578.3 41 21
199 Endogenous MAGEA3/A6 NM_005362.3 470 10
200 Endogenous ARID1A NM_006015.4 316 291
201 Endogenous CD48 NM_001778.3 26 11
202 Endogenous GZMA NM_006144.3 13 19
203 Endogenous ICOSLG NM_015259.4 130 92
204 Endogenous PIK3R5 NM_014308.3 37 39
205 Endogenous GZMM NM_005317.2 13 14
206 Endogenous WNT5A NM_003392.3 109 25
207 Endogenous TLR4 NR_024168.1 79 103
208 Endogenous GZMB NM_004131.4 8 5
209 Endogenous PARP9 NM_001146103.1 445 176
210 Endogenous LY96 NM_001195797.1 154 147
211 Endogenous RAD50 NM_005732.3 612 1386
212 Endogenous MX1 NM_001144925.2 451 127
213 Endogenous CENPF NM_016343.3 126 11
214 Endogenous SELL NM_000655.4 9 24
215 Endogenous TNFSF10 NM_003810.3 378 277
216 Endogenous IL12RB2 NM_001319233.1 23 10
217 Endogenous CXCL9 NM_002416.2 22 26
218 Endogenous TRAT1 NM_016388.3 5 13
219 Endogenous STC1 NM_003155.2 61 129
220 Endogenous IL2RB NM_000878.2 18 19
221 Endogenous LILRB4 NM_001278426.3 44 69
222 Endogenous SOX2 NM_003106.2 9 12
223 Endogenous HCK NM_001172129.1 55 59
224 Endogenous WNT2B NM_001291880.1 20 43
225 Endogenous IL1B NM_000576.2 19 15
226 Endogenous TLR1 NM_003263.3 60 53
227 Endogenous CCL22 NM_002990.3 15 11
228 Endogenous ICAM2 NM_000873.3 19 36
229 Endogenous MAP3K12 NM_006301.3 59 76
230 Endogenous JAG1 NM_000214.2 119 178
231 Endogenous CCL3/L1 NM_021006.5 122 19
232 Endogenous SOCS1 NM_003745.1 39 12
233 Endogenous BCL2 NM_000633.2 198 472
234 Endogenous MAP3K8 NM_001244134.1 213 69
235 Endogenous MMP1 NM_002421.2 47 24
236 Endogenous CMKLR1 NM_004072.2 40 118
237 Endogenous TNFRSF17 NM_001192.2 10 18
238 Endogenous TLR8 NM_138636.4 21 26
239 Endogenous TPM1 NM_000366.5 580 406
240 Endogenous CXorf36 NM_024689.2 48 141
241 Endogenous NLRP3 NM_001079821.2 16 17
242 Endogenous DEFB134 NM_001302695.1 16 23
243 Endogenous HLA-DQA2 NM_020056.4 25 25
244 Endogenous CX3CR1 NM_001171171.1 11 82
245 Endogenous APLNR NM_005161.4 7 41
246 Endogenous MXI1 NM_001008541.1 88 73
247 Endogenous FZD9 NM_003508.2 16 15
248 Endogenous COL4A5 NM_000495.4 101 354
249 Endogenous FCAR NM_133278.2 13 11
250 Endogenous BRCA2 NM_000059.3 85 78
251 Endogenous SFRP4 NM_003014.2 163 447
252 Endogenous TLR3 NM_003265.2 89 43
253 Endogenous IL2RG NM_000206.1 21 22
254 Endogenous CD84 NM_001184879.1 60 87
255 Endogenous HLA-DPA1 NM_033554.2 330 591
256 Endogenous RBL2 NM_001323611.1 427 1334
257 Endogenous CCL18 NM_002988.3 135 170
258 Endogenous IRF3 NM_001197122.1 126 104
259 Endogenous TNFRSF8 NM_001243.3 4 9
260 Endogenous KIR3DL2 NM_006737.2 5 7
261 Endogenous TNFSF13 NM_003808.3 55 52
262 Endogenous CLECL1 NM_172004.3 18 27
263 Endogenous TNFRSF10B NM_003842.3 59 30
264 Endogenous MAGEC2 NM_016249.3 16 14
265 Endogenous CDKN2A NM_000077.4 91 131
266 Endogenous ADM NM_001124.2 178 75
267 Endogenous PNOC NM_001284244.1 35 37
268 Endogenous CD247 NM_198053.2 39 40
269 Endogenous PTPRC NM_080921.3 61 48
270 Endogenous OAS3 NM_006187.3 756 156
271 Endogenous LAG3 NM_002286.5 86 58
272 Endogenous FOSL1 NM_005438.3 118 108
273 Endogenous EOMES NM_001278182.1 38 32
274 Endogenous IL10RA NM_001558.2 76 64
275 Endogenous WDR76 NM_024908.3 70 89
276 Endogenous GPC4 NM_001448.2 51 41
277 Endogenous SLAMF7 NM_021181.3 35 56
278 Endogenous RSAD2 NM_080657.4 1136 147
279 Endogenous TLR5 NM_003268.5 88 74
280 Endogenous VEGFA NM_001171623.1 1871 269
281 Endogenous COL5A1 NM_000093.4 710 331
282 Endogenous CD3D NM_000732.4 41 59
283 Endogenous FBP1 NM_001127628.1 226 779
284 Endogenous ERO1A NM_014584.2 1094 736
285 Endogenous CCL21 NM_002989.2 18 33
286 Endogenous E2F3 NM_001243076.2 174 130
287 Endogenous LDHA NM_001135239.1 7634 526
288 Endogenous MS4A1 NM_021950.3 32 67
289 Endogenous CD69 NM_001781.2 45 47
290 Endogenous SERPINB5 NM_002639.4 46 33
291 Endogenous FAP NM_004460.2 331 136
292 Endogenous ITGA2 NM_002203.3 160 21
293 Endogenous SIGLEC5 NM_003830.3 16 22
294 Endogenous SIRPB2 NM_001134836.1 21 21
295 Endogenous EPM2AIP1 NM_014805.3 333 166
296 Endogenous FGF18 NM_003862.2 12 19
297 Endogenous HRAS NM_005343.3 134 201
298 Endogenous CCND1 NM_053056.2 823 2876
299 Endogenous LAMB3 NM_000228.2 63 43
300 Endogenous ID4 NM_001546.3 24 52
301 Endogenous CCL4 NM_002984.2 53 48
302 Endogenous GZMH NM_033423.3 15 14
303 Endogenous API5 NM_001142930.1 525 456
304 Endogenous PTGER4 NM_000958.2 32 42
305 Endogenous ITGB8 NM_002214.2 39 247
306 Endogenous TNKS NM_003747.2 120 166
307 Endogenous B2M NM_004048.2 8147 3820
308 Endogenous TP53 NM_000546.2 118 102
309 Endogenous MAGEB2 NM_002364.4 16 10
310 Endogenous LYZ NM_000239.2 298 420
311 Endogenous NCAM1 NM_000615.6 9 83
312 Endogenous TCL1A NM_001098725.1 6 4
313 Endogenous HDC NM_002112.3 7 23
314 Endogenous CD27 NM_001242.4 15 30
315 Endogenous SBNO2 NM_001100122.1 181 146
316 Endogenous PECAM1 NM_000442.4 251 571
317 Endogenous SERPINH1 NM_001207014.1 131 58
318 Endogenous SPP1 NM_000582.2 3435 448
319 Endogenous EGFR NM_005228.3 57 50
320 Endogenous CASP8 NM_001228.4 35 24
321 Endogenous CCNA1 NM_001111045.1 15 11
322 Endogenous TNFAIP3 NM_001270508.1 36 18
323 Endogenous CDC25C NM_001790.4 33 17
324 Endogenous CXCR6 NM_006564.1 16 20
325 Endogenous DLL1 NM_005618.3 13 29
326 Endogenous OAS1 NM_001032409.1 1120 150
327 Endogenous HLA-DQB1 NM_002123.3 59 7
328 Endogenous ROBO4 NM_019055.5 26 52
329 Endogenous NFKB1 NM_003998.3 242 126
330 Endogenous IFI27 NM_005532.3 11191 2564
331 Endogenous HLA-DMB NM_002118.3 104 176
332 Endogenous CDKN1C NM_000076.2 43 224
333 Endogenous CEP55 NM_018131.3 70 9
334 Endogenous ARG1 NM_000045.3 13 16
335 Endogenous PLOD2 NM_182943.2 642 217
336 Endogenous LAIR1 NM_001289023.2 36 43
337 Endogenous SHC2 NM_012435.2 40 159
338 Endogenous STAT3 NM_003150.3 997 849
339 Endogenous CD45RO NM_080921.3 122 77
340 Endogenous CD2 NM_001767.3 105 68
341 Endogenous IL7R NM_002185.3 31 16
342 Endogenous FLNB NM_001164319.1 673 1468
343 Endogenous PSMB5 NM_001130725.1 528 445
344 Endogenous SLC1A5 NM_001145144.1 195 749
345 Endogenous RICTOR NM_001285439.1 250 1094
346 Endogenous ZAP70 NM_001079.3 34 25
347 Endogenous TNFAIP6 NM_007115.3 151 57
348 Endogenous BTLA NM_001085357.1 8 14
349 Endogenous RELA NM_021975.3 156 123
350 Endogenous MMP7 NM_002423.3 184 13
351 Endogenous TCF3 NM_003200.3 201 105
352 Endogenous IRF8 NM_002163.2 40 34
353 Endogenous NOS2 NM_000625.4 6 10
354 Endogenous A2M NM_000014.4 694 1423
355 Endogenous CCL20 NM_001130046.1 20 8
356 Endogenous MKI67 NM_002417.2 308 30
357 Endogenous IFNGR1 NM_000416.2 202 440
358 Endogenous INHBA NM_002192.2 161 80
359 Endogenous WNT5B NM_030775.2 35 17
360 Endogenous CXCL5 NM_002994.4 21 19
361 Endogenous SOX10 NM_006941.3 8 9
362 Endogenous EGR1 NM_001964.2 127 162
363 Endogenous STAT4 NM_001243835.1 23 34
364 Endogenous IFIT3 NM_001031683.3 490 67
365 Endogenous GMIP NM_001288998.1 12 18
366 Endogenous ARNT2 NM_014862.3 153 157
367 Endogenous UBE2C NM_007019.2 188 13
368 Endogenous CHUK NM_001278.4 222 211
369 Endogenous GHR NM_000163.2 64 140
370 Endogenous TPI1 NM_000365.5 2927 1072
371 Endogenous HAVCR2 NM_032782.3 81 52
372 Endogenous GOT2 NM_002080.3 505 733
373 Endogenous PIK3CA NM_006218.2 103 176
374 Endogenous TNFSF9 NM_003811.3 7 16
375 Endogenous IDO1 NM_002164.5 24 17
376 Endogenous APOE NM_000041.2 553 284
377 Endogenous LILRB2 NM_001278405.1 27 29
378 Endogenous PARP4 NM_006437.3 283 183
379 Endogenous PFKM NM_000289.5 133 172
380 Endogenous THY1 NM_006288.3 305 265
381 Endogenous SAMD9 NM_017654.3 497 88
382 Endogenous TGFB1 NM_000660.4 420 421
383 Endogenous CD8A NM_001768.6 24 35
384 Endogenous SELE NM_000450.2 23 18
385 Endogenous CDKN2B NM_004936.3 77 101
386 Endogenous CD5 NM_001346456.1 18 24
387 Endogenous HLA-A NM_002116.7 1921 529
388 Endogenous FZD8 NM_031866.1 21 462
389 Endogenous BCL2L1 NM_001191.3 231 333
390 Endogenous TNFRSF9 NM_001561.5 22 9
391 Endogenous XCL1/2 NM_002995.2 37 13
392 Endogenous MAGEA4 NM_001011548.1 10 12
393 Endogenous PMS2 NM_000535.6 249 281
394 Endogenous KLRD1 NM_002262.3 18 15
395 Endogenous NFATC2 NM_173091.2 73 81
396 Endogenous VEGFB NM_003377.3 154 98
397 Endogenous CDC20 NM_001255.1 52 16
398 Endogenous OTOA NM_001161683.1 11 16
399 Endogenous TPSAB1/B2 NM_003294.3 84 148
400 Endogenous P4HA1 NM_000917.3 415 73
401 Endogenous P2RY13 NM_023914.2 9 33
402 Endogenous EXO1 NM_006027.3 37 20
403 Endogenous CD70 NM_001252.3 6 20
404 Endogenous DDB2 NM_000107.2 166 137
405 Endogenous NDUFA4L2 NM_020142.3 26 45
406 Endogenous IFITM1 NM_003641.3 3082 426
407 Endogenous IFNAR1 NM_000629.2 220 378
408 Endogenous TREM1 NM_001242589.2 44 13
409 Endogenous CXCL13 NM_006419.2 66 54
410 Endogenous TWIST2 NM_001271893.3 6 9
411 Endogenous HLA-DRB1 NM_002124.3 572 309
412 Endogenous FGFR1 NM_001174064.1 286 248
413 Endogenous TBXAS1 NM_001061.4 40 121
414 Endogenous NCR1 NM_001145457.2 5 9
415 Endogenous SOX11 NM_003108.3 25 17
416 Endogenous TLR2 NM_001318787.1 129 82
417 Endogenous TWF1 NM_002822.4 541 753
418 Endogenous CCL5 NM_002985.2 64 47
419 Endogenous ITGAL NM_002209.2 22 89
420 Endogenous MYCT1 NM_025107.2 23 36
421 Endogenous CD96 NM_005816.4 13 17
422 Endogenous PROM1 NM_001145847.1 20 12
423 Endogenous OASL NM_003733.2 158 15
424 Endogenous IFNG NM_000619.2 11 14
425 Endogenous BATF3 NM_018664.2 23 18
426 Endogenous EZH2 NM_004456.4 107 27
427 Endogenous IRF5 NM_002200.3 34 24
428 Endogenous PCK2 NM_001018073.2 137 184
429 Endogenous EPCAM NM_002354.2 498 438
430 Endogenous CD19 NM_001770.4 19 32
431 Endogenous GBP4 NM_052941.4 93 77
432 Endogenous MSH6 NM_000179.2 72 76
433 Endogenous TNFRSF11B NM_002546.3 30 26
434 Endogenous NOTCH1 NM_017617.3 54 71
435 Endogenous CASP9 XM_011542270.1 40 43
436 Endogenous RAD51C NM_058216.2 45 125
437 Endogenous HLA-DMA NM_006120.3 333 350
438 Endogenous SFRP1 NM_003012.3 29 78
439 Endogenous MAGEA1 NM_004988.4 23 14
440 Endogenous ENTPD1 NM_001098175.1 107 195
441 Endogenous ROCK1 NM_005406.2 94 135
442 Endogenous FCGR2A NM_021642.3 184 288
443 Endogenous NGFR NM_002507.3 23 44
444 Endogenous ALDOC NM_005165.2 419 473
445 Endogenous CCNE1 NM_001238.1 59 22
446 Endogenous ITGAX NM_000887.4 115 104
447 Endogenous BLM NM_000057.3 60 52
448 Endogenous MLANA NM_005511.1 20 18
449 Endogenous FCGR1A NM_000566.3 49 81
450 Endogenous CD47 NM_001777.3 925 409
451 Endogenous CSF2 NM_000758.3 13 19
452 Endogenous CDH5 NM_001795.3 31 85
453 Endogenous SLC7A5 NM_003486.6 316 174
454 Endogenous GIMAP4 NM_018326.2 103 177
455 Endogenous HIF1A NM_181054.2 705 384
456 Endogenous CDK2 NM_001290230.1 188 98
457 Endogenous PDCD1 NM_005018.1 12 14
458 Endogenous ATF3 NM_001674.3 66 31
459 Endogenous TIE1 NM_005424.4 40 81
460 Endogenous CD44 NM_001001392.1 630 188
461 Endogenous ALDOA NM_000034.3 4299 4732
462 Endogenous FAS NM_000043.3 35 14
463 Endogenous MRE11 NM_001330347.1 156 188
464 Endogenous IL10 NM_000572.2 14 12
465 Endogenous BMP2 NM_001200.3 10 240
466 Endogenous BAX NM_004324.3 291 159
467 Endogenous EIF5AL1 NM_001099692.1 5 14
468 Endogenous KIT NM_000222.2 16 36
469 Endogenous CDK6 NM_001145306.1 27 35
470 Endogenous SPIB NM_003121.3 10 10
471 Endogenous PFKFB3 NM_004566.3 36 33
472 Endogenous CXCL12 NM_199168.3 18 59
473 Endogenous CSF3 NM_000759.3 7 10
474 Endogenous KIR2DL3 NM_015868.2 17 22
475 Endogenous CD40 NM_001250.5 40 67
476 Endogenous IRF1 NM_002198.2 223 158
477 Endogenous MGMT NM_002412.3 183 299
478 Endogenous GLUD1 NM_005271.2 334 648
479 Endogenous IFI35 NM_005533.4 240 192
480 Endogenous PF4 NM_002619.3 14 22
481 Endogenous GPSM3 NM_001276501.1 39 69
482 Endogenous SLC2A1 NM_006516.2 72 42
483 Endogenous IL2 NM_000586.2 15 21
484 Endogenous SNAI1 NM_005985.3 60 62
485 Endogenous CTNNB1 NM_001098209.1 1955 1539
486 Endogenous NOTCH2 NM_024408.3 351 206
487 Endogenous NFKB2 NM_001077494.3 124 77
488 Endogenous IL33 NM_033439.3 18 53
489 Endogenous TREM2 NM_018965.3 64 98
490 Endogenous LAMC2 NM_005562.2 43 30
491 Endogenous AQP9 NM_001320635.1 45 24
492 Endogenous PRKCA NM_002737.2 17 30
493 Endogenous TSLP NM_033035.4 15 17
494 Endogenous HLA-DOB NM_002120.3 9 33
495 Endogenous ANGPTL4 NM_001039667.2 93 10
496 Endogenous TNFRSF25 NM_148970.1 43 94
497 Endogenous MS4A4A NM_001243266.1 84 124
498 Endogenous CLEC5A NM_013252.2 39 29
499 Endogenous ITGAM NM_000632.3 19 15
500 Endogenous MMP9 NM_004994.2 57 77
501 Endogenous CD7 NM_006137.6 14 16
502 Endogenous VHL NM_198156.1 70 73
503 Endogenous OLFML2B NM_015441.1 45 59
504 Endogenous IL6 NM_000600.3 24 21
505 Endogenous TNFRSF1A NM_001065.2 330 342
506 Endogenous DKK1 NM_012242.2 14 12
507 Endogenous FANCA NM_001018112.1 38 25
508 Endogenous TNF NM_000594.3 58 38
509 Endogenous LTB NM_002341.1 18 23
510 Endogenous PPARGC1B NM_001172699.1 25 41
511 Endogenous RPS6KB1 NM_001272042.1 133 819
512 Endogenous CD38 NM_001775.2 24 20
513 Endogenous DTX3L NM_138287.3 598 351
514 Endogenous TMEM173 NM_198282.1 279 227
515 Endogenous NEIL1 NM_024608.2 66 51
516 Endogenous HELLS NM_001289067.1 168 65
517 Endogenous TGFBR1 NM_001130916.2 206 386
518 Endogenous MB21D1 NM_138441.2 45 84
519 Endogenous CCR2 NM_001123041.2 17 12
520 Endogenous MSH2 NM_000251.1 227 193
521 Endogenous RAD51 NM_133487.3 26 9
522 Endogenous TNFRSF18 NM_148901.1 26 23
523 Endogenous FCGR3A/B NM_000570.4 325 145
524 Endogenous STAT1 NM_007315.3 2167 456
525 Endogenous CTSS NM_004079.3 430 385
526 Endogenous PDK1 NM_002610.3 435 252
527 Endogenous ITGAV NM_001144999.2 612 1041
528 Endogenous ANGPT1 NM_001199859.1 21 53
529 Endogenous BCL6B NM_181844.3 15 43
530 Endogenous CDH2 NM_001792.3 48 35
531 Endogenous CSF3R NM_000760.3 166 124
532 Endogenous RELB NM_006509.3 82 56
533 Endogenous CXCL16 NM_001100812.1 109 124
534 Endogenous IL6R NM_000565.3 27 71
535 Endogenous PDGFA NM_033023.4 35 47
536 Endogenous PIK3R1 NM_001242466.1 119 173
537 Endogenous HK1 NM_000188.2 499 292
538 Endogenous AXL NM_001699.4 65 75
539 Endogenous HK2 NM_000189.4 658 329
540 Endogenous PDGFRB NM_002609.3 347 409
541 Endogenous FADD NM_003824.3 92 489
542 Endogenous CD74 NM_001025159.2 2455 2542
543 Endogenous RIPK2 NM_003821.5 124 176
544 Endogenous CD45RB ENST00000367367.1 45 38
545 Endogenous BAD NM_004322.3 86 67
546 Endogenous PKM NM_001206796.2 5714 2857
547 Endogenous KLRB1 NM_002258.2 15 20
548 Endogenous ADORA2A NM_000675.5 128 33
549 Endogenous IFIT1 NM_001270930.1 1506 116
550 Endogenous UBE2T NM_014176.1 46 26
551 Endogenous RPL23 NM_000978.3 3210 5939
552 Endogenous ARG2 NM_001172.3 32 70
553 Endogenous TGFBR2 NM_001024847.2 114 238
554 Endogenous CRABP2 NM_001199723.1 2655 1783
555 Endogenous BLK NM_001330465.1 18 18
556 Endogenous CCL14 NM_032962.4 41 416
557 Endogenous CCNB1 NM_031966.2 421 135
558 Endogenous STAT2 NM_005419.2 998 514
559 Endogenous IKBKB NM_001190720.2 238 260
560 Endogenous ZEB2 NM_001171653.1 214 283
561 Endogenous LRRC32 NM_005512.2 85 142
562 Endogenous IL22RA1 NM_021258.2 33 33
563 Endogenous ELOB NM_007108.2 42 54
564 Endogenous ITGA1 NM_181501.1 70 92
565 Endogenous IL24 NM_001185158.1 20 20
566 Endogenous PVRIG NM_024070.3 49 41
567 Endogenous RB1 NM_000321.2 252 229
568 Endogenous SRP54 NM_001146282.1 170 175
569 Endogenous ICAM3 NM_002162.3 90 79
570 Endogenous CCR5 NM_000579.3 49 44
571 Endogenous CTLA4 NM_001037631.2 25 19
572 Endogenous GLS NM_014905.4 68 69
573 Endogenous ITGAE NM_002208.4 120 219
574 Endogenous MET NM_000245.2 110 96
575 Endogenous WNT3A NM_033131.3 18 30
576 Endogenous TYMP NM_001113755.2 752 388
577 Endogenous IFI16 NM_001206567.1 207 169
578 Endogenous PVR NM_001135768.2 68 77
579 Endogenous P4HA2 NM_001017973.1 157 314
580 Endogenous BRIP1 NM_032043.2 71 49
581 Endogenous ESR1 NM_000125.2 23 1154
582 Endogenous DAB2 NM_001244871.1 120 129
583 Endogenous DUSP1 NM_004417.3 111 719
584 Endogenous CD8B NM_172213.2 30 31
585 Endogenous ACVR1C NM_145259.2 29 33
586 Endogenous IL15 NM_000585.4 25 26
587 Endogenous KIR3DL1 NM_001322168.1 19 21
588 Endogenous CDH1 NM_004360.3 3142 758
589 Endogenous HES1 NM_005524.2 267 152
590 Endogenous IHH NM_002181.2 18 28
591 Endogenous CCL19 NM_006274.2 24 35
592 Endogenous C2 NM_000063.5 107 44
593 Endogenous TLR7 NM_016562.3 23 29
594 Endogenous IL2RA NM_000417.2 19 14
595 Endogenous PRKAA2 NM_006252.3 27 62
596 Endogenous COL11A2 NM_001163771.1 13 14
597 Endogenous TNFRSF10D NM_003840.4 22 30
598 Endogenous SIGLEC8 NM_014442.2 13 15
599 Endogenous PC NM_000920.3 103 108
600 Endogenous IL17A NM_002190.2 24 20
601 Endogenous GLI1 NM_005269.2 19 18
602 Endogenous GNG4 NM_001098721.1 37 51
603 Endogenous LDHB NM_001174097.2 572 465
604 Endogenous DTX4 NM_015177.1 78 29
605 Endogenous CD3G NM_000073.2 14 16
606 Endogenous S100A8 NM_002964.4 2954 16
607 Endogenous ZC3H12A NM_025079.2 29 30
608 Endogenous IER3 NM_003897.3 280 817
609 Endogenous CD4 NM_000616.4 29 33
610 Endogenous S100A12 NM_005621.1 21 18
611 Endogenous CD6 NM_001254751.1 16 22
612 Endogenous CD163 NM_203416.2 144 83
613 Endogenous DUSP2 NM_004418.3 22 25
614 Endogenous HERC6 NM_001165136.1 158 56
615 Endogenous MRC1 NM_002438.2 23 64
616 Endogenous DLL4 NM_019074.2 36 53
617 Endogenous SAMSN1 NM_001256370.1 63 69
618 Endogenous CD28 NM_001243077.1 19 41
619 Endogenous TAP2 NM_018833.2 321 120
620 Endogenous ICOS NM_012092.3 6 14
621 Endogenous TNFSF12 NM_003809.2 45 100
622 Endogenous IFITM2 NM_006435.2 956 569
623 Endogenous DNMT1 NM_001130823.2 319 236
624 Endogenous TNFSF8 NM_001244.3 32 28
625 Endogenous TGFB2 NM_001135599.3 48 49
626 Endogenous TMEM140 NM_018295.3 64 41
627 Endogenous COL11A1 NM_001854.3 514 133
628 Endogenous GIMAP6 NR_024115.1 20 40
629 Endogenous IRF4 NM_002460.1 33 79
630 Endogenous BNIP3 NM_004052.3 445 240
631 Endogenous FPR3 NM_002030.4 225 79
632 Endogenous HLA-C NM_002117.4 1786 695
633 Endogenous VEGFC NM_005429.4 135 69
634 Endogenous SIGLEC1 NM_023068.3 58 66
635 Endogenous BID NM_001196.3 40 34
636 Endogenous MAPK10 NM_001318067.1 62 76
637 Endogenous FCN1 NM_002003.4 16 24
638 Endogenous H2AFX NM_002105.2 71 33
639 Endogenous CBLC NM_001130852.1 34 35
640 Endogenous CASP3 NM_032991.2 224 225
641 Endogenous PIAS4 NM_015897.2 200 62
642 Endogenous HLA-DRA NM_019111.3 1430 2507
643 Endogenous ULBP2 NM_025217.2 19 24
644 Endogenous CASP1 NM_001223.4 71 77
645 Endogenous MS4A2 NM_000139.3 18 19
646 Endogenous HSD11B1 NM_181755.2 21 24
647 Endogenous GAS1 NM_002048.2 47 41
648 Endogenous FUT4 NM_002033.3 41 42
649 Endogenous CSF1 NM_000757.5 59 71
650 Endogenous FAM30A NR_026800.2 23 25
651 Endogenous ITPK1 NM_001142593.2 273 1750
652 Endogenous BCAT1 NM_005504.6 81 26
653 Endogenous CD80 NM_005191.3 43 20
654 Endogenous C1QB NM_000491.3 302 312
655 Endogenous RELN NM_005045.3 18 27
656 Endogenous ICAM5 NM_003259.3 16 14
657 Endogenous MAML2 NM_032427.1 39 53
658 Endogenous OLR1 NM_002543.3 107 73
659 Endogenous NFKBIE NM_004556.2 58 43
660 Endogenous WNT11 XM_011545241.2 20 19
661 Endogenous LILRA3 NM_001172654.2 28 31
662 Endogenous TNFSF13B NM_001145645.2 51 81
663 Endogenous TDO2 NM_005651.3 102 27
664 Endogenous MAP3K5 NM_005923.3 64 125
665 Endogenous HLA-F NM_001098479.1 303 151
666 Endogenous CD3E NM_000733.3 28 42
667 Endogenous RRM2 NM_001034.1 714 44
668 Endogenous C7 NM_000587.2 33 81
669 Endogenous TNFRSF14 NM_003820.3 203 197
670 Endogenous FCGRT NM_004107.4 216 403
671 Endogenous WNT2 NM_003391.2 41 24
672 Endogenous MICB NM_005931.3 40 21
673 Endogenous HMGA1 NM_145902.2 253 110
674 Endogenous IL21R NM_021798.3 19 13
675 Endogenous CD300A NM_001256841.1 38 34
676 Endogenous TWIST1 NM_000474.3 160 93
677 Endogenous IL1RN NM_000577.3 34 19
678 Endogenous CXCL1 NM_001511.3 18 9
679 Endogenous SFXN1 NM_001322977.1 662 1899
680 Endogenous GNLY NM_012483.3 11 36
681 Endogenous NID2 NM_007361.3 231 168
682 Endogenous NECTIN1 NM_002855.4 180 90
683 Endogenous SERPINA1 NM_001127702.1 164 1414
684 Endogenous PDGFB NM_002608.2 45 51
685 Endogenous HLA-B NM_005514.6 4911 2885
686 Endogenous VCAM1 NM_001078.3 190 124
687 Endogenous HLA-DPB1 NM_002121.5 383 805
688 Endogenous HLA-DOA NM_002119.3 29 49
689 Endogenous GBP2 NM_004120.4 128 77
690 Endogenous ATM NM_000051.3 343 396
691 Endogenous PSMB8 NM_004159.4 275 176
692 Endogenous MLH1 NM_000249.2 173 132
693 Endogenous PLA1A NM_015900.2 23 31
694 Endogenous NT5E NM_002526.3 109 52
695 Endogenous PALMD NM_017734.4 23 74
696 Endogenous UBA7 NM_003335.2 148 83
697 Endogenous PIK3CD NM_001350234.1 36 36
698 Endogenous NOD2 NM_022162.1 36 40
699 Endogenous CEACAM3 NM_001277163.2 33 39
700 Endogenous RIPK3 NM_006871.3 43 76
701 Endogenous IL1R2 NR_048564.1 16 6
702 Endogenous JAK1 NM_002227.1 316 413
703 Endogenous ENO1 NM_001428.3 5271 843
704 Endogenous LILRA1 NM_001278318.1 27 23
705 Endogenous BBS1 NM_024649.4 83 97
706 Endogenous MYD88 NM_002468.3 214 176
707 Endogenous CXCR3 NM_001142797.1 13 20
708 Endogenous CD1C NM_001765.2 9 22
709 Endogenous TLR9 NM_017442.2 20 28
710 Endogenous CCL7 NM_006273.3 67 23
711 Endogenous CPA3 NM_001870.2 68 142
712 Endogenous SH2D1A NM_001114937.2 20 29
713 Endogenous CCR4 NM_005508.4 33 24
714 Endogenous HDAC4 NM_006037.3 46 33
715 Endogenous POLD1 NM_001256849.1 44 41
716 Endogenous PTPN11 NM_001330437.1 610 922
717 Endogenous JAK2 NM_004972.2 152 236
718 Endogenous WNT10A NM_025216.2 17 16
719 Endogenous ITGB2 NM_000211.3 166 174
720 Endogenous TYMS NM_001071.1 269 45
721 Endogenous KAT2B NM_003884.4 125 310
722 Endogenous ITGA6 NM_001316306.1 65 246
723 Endogenous TBX21 NM_013351.1 24 28
724 Endogenous BRCA1 NM_007294.3 42 70
725 Endogenous COL17A1 NM_000494.3 51 35
726 Endogenous BIRC3 NM_001165.4 20 31
727 Endogenous KRAS NM_004985.3 151 181
728 Endogenous IL11RA NM_147162.1 39 89
729 Endogenous SIRPA NM_001040023.1 101 98
730 Endogenous CEBPB NM_005194.3 357 267
731 Endogenous VTCN1 NM_001253849.1 755 68
732 Endogenous SGK1 NM_005627.3 161 110
733 Endogenous NLRC5 NM_032206.4 135 66
734 Endogenous CCL8 NM_005623.2 271 46
735 Endogenous TRAF1 NM_001190945.1 25 82
736 Endogenous ADAM12 NM_003474.5 523 104
737 Endogenous MMRN2 NM_024756.2 61 121
738 Endogenous PTGS2 NM_000963.1 29 40
739 Endogenous SMAD5 NM_005903.5 224 685
740 Endogenous LCK NM_005356.4 34 46
741 Endogenous ITGB3 NM_000212.2 45 73
742 Endogenous FCGR2B NM_001002273.1 99 88
743 Endogenous NRAS NM_002524.4 294 248
744 Endogenous IL34 NM_001172771.1 40 55
745 Endogenous LAMA1 NM_005559.3 57 43
746 Endogenous CLEC4E NM_014358.3 34 33
747 Endogenous IL18R1 NM_001282399.1 40 37
748 Endogenous MFNG NM_002405.3 98 29
749 Endogenous TTC30A NM_152275.3 124 170
750 Endogenous TNFRSF10C NM_003841.3 73 54
751 Positive POS_C(8) ERCC_00002.1 3852 4739
752 Positive POS_A(128) ERCC_00117.1 36727 43726
753 Positive POS_F(0.125) ERCC_00034.1 75 85
754 Positive POS_D(2) ERCC_00092.1 725 898
755 Positive POS_B(32) ERCC_00112.1 14523 17129
756 Positive POS_E(0.5) ERCC_00035.1 150 158
757 Negative NEG_C(0) ERCC_00019.1 27 29
758 Negative NEG_D(0) ERCC_00076.1 8 15
759 Negative NEG_E(0) ERCC_00098.1 24 20
760 Negative NEG_A(0) ERCC_00096.1 17 29
761 Negative NEG_H(0) ERCC_00154.1 12 11
762 Negative NEG_G(0) ERCC_00144.1 14 7
763 Negative NEG_F(0) ERCC_00126.1 39 39
764 Negative NEG_B(0) ERCC_00041.1 20 17
765 Housekeeping UBB NM_018955.3 3440 4712
766 Housekeeping PUM1 NM_001020658.1 615 750
767 Housekeeping TLK2 NM_006852.3 144 418
768 Housekeeping DNAJC14 NM_032364.5 201 244
769 Housekeeping SF3A1 NM_005877.4 315 313
770 Housekeeping POLR2A NM_000937.2 460 550
771 Housekeeping SDHA NM_004168.3 339 570
772 Housekeeping STK11IP NM_052902.2 103 100
773 Housekeeping NRDE2 NM_017970.3 179 336
774 Housekeeping TBP NM_001172085.1 117 230
775 Housekeeping OAZ1 NM_004152.2 2242 1825
776 Housekeeping TBC1D10B NM_015527.3 92 86
777 Housekeeping GUSB NM_000181.1 146 177
778 Housekeeping PSMC4 NM_006503.2 209 359
779 Housekeeping TFRC NM_003234.1 489 142
780 Housekeeping ABCF1 NM_001090.2 170 258
781 Housekeeping TMUB2 NM_177441.2 82 172
782 Housekeeping MRPL19 NM_014763.3 232 223
783 Housekeeping G6PD NM_000402.4 92 199
784 Housekeeping ERCC3 NM_000122.1 454 403
pre_count_2 post_count_2 pre_count_3 post_count_3 pre_count_4 post_count_4
1 324 23 1465 24 87 13
2 2138 570 529 105 55 102
3 31 49 35 9 110 12
4 135 751 123 103 31 40
5 5611 15209 8545 3362 1618 2285
6 1564 361 257 197 73 129
7 3997 3936 2597 566 232 121
8 83 97 124 38 46 54
9 4795 5862 7387 779 888 882
10 470 388 292 65 107 122
11 167 59 219 52 32 216
12 10 20 11 16 12 12
13 85 68 26 21 20 31
14 1110 872 1059 236 75 142
15 4017 2217 2339 1203 467 534
16 746 85 36 166 33 34
17 1756 1347 799 349 512 122
18 452 21 798 145 27 31
19 184 54 105 24 16 25
20 266 247 424 92 45 70
21 18 36 23 7 25 11
22 50 45 47 51 25 43
23 476 580 974 88 263 122
24 751 876 863 315 189 284
25 187 614 645 33 78 61
26 57 86 106 13 27 22
27 1844 3676 2301 522 346 334
28 247 284 304 68 98 92
29 610 629 899 206 287 149
30 66 31 17 24 12 17
31 410 328 189 53 40 33
32 72 96 116 20 16 23
33 281 1309 1339 391 472 433
34 2115 1703 2727 545 700 738
35 3245 4603 3999 1976 1167 1515
36 4334 14695 8730 3523 1809 2069
37 78 194 332 45 149 53
38 777 526 892 202 287 175
39 26951 12249 20207 3808 4053 4854
40 1414 1819 3115 629 1002 1826
41 626 385 438 167 36 81
42 735 343 514 93 127 114
43 7977 783 4406 675 582 414
44 627 415 381 88 114 74
45 81 170 294 127 297 154
46 424 226 197 47 96 118
47 464 339 225 127 121 52
48 42 77 61 17 19 22
49 285 119 230 41 38 55
50 564 385 484 109 63 55
51 471 1063 1112 152 235 180
52 31 21 14 7 8 12
53 1446 1225 2188 474 871 362
54 73 57 49 11 30 138
55 149 134 247 40 20 181
56 83 15 10 16 23 11
57 32 17 30 20 23 15
58 96 114 86 14 20 16
59 1499 974 970 435 441 284
60 36 49 94 22 59 17
61 116 65 48 21 43 28
62 802 1827 1883 195 175 199
63 175 193 282 78 82 78
64 1731 1722 1377 188 84 166
65 67 108 78 23 34 45
66 693 1869 1591 237 1220 276
67 696 370 310 68 43 94
68 214 662 322 41 67 64
69 233 537 435 45 44 38
70 36 43 35 28 32 42
71 74 122 108 44 112 61
72 119 266 192 50 29 33
73 16 28 15 13 15 20
74 227 92 64 57 31 80
75 49 38 64 28 19 17
76 268 308 493 56 246 93
77 385 180 182 43 64 39
78 384 280 430 43 37 49
79 101 326 150 45 80 47
80 578 2098 1190 90 102 228
81 664 498 549 107 68 97
82 1535 1133 1784 259 332 268
83 125 95 105 29 28 31
84 23 35 47 26 90 12
85 1231 908 1167 251 285 109
86 450 527 1634 215 106 173
87 27 56 44 14 25 22
88 1068 338 222 95 268 234
89 1238 1428 5217 909 3675 599
90 967 1147 1404 501 377 135
91 146 113 315 56 42 219
92 2011 83 14 16 11 20
93 630 1101 944 164 122 197
94 386 123 41 53 27 43
95 681 574 695 151 234 202
96 200 271 409 101 170 64
97 8 15 10 20 20 15
98 249 108 135 76 41 36
99 177 23 11 25 11 17
100 49 45 29 17 17 16
101 170 121 149 33 75 42
102 327 239 526 53 349 108
103 2299 3846 3535 458 372 589
104 1081 585 904 154 110 141
105 97 21 25 24 32 16
106 4796 3354 4470 628 1618 996
107 877 657 790 182 165 292
108 761 529 668 220 242 191
109 900 1884 1322 247 261 170
110 52 50 71 13 34 15
111 21 38 22 19 13 14
112 109 176 166 36 29 29
113 859 894 1205 165 438 262
114 60 132 133 42 63 40
115 398 605 638 103 238 51
116 714 812 1063 190 96 110
117 37 118 256 85 30 28
118 771 628 409 160 375 333
119 14 5 10 9 13 8
120 151 252 319 307 136 153
121 36 50 56 33 22 20
122 117 136 126 63 137 115
123 162 389 143 77 38 79
124 521 398 292 130 148 162
125 366 228 1456 180 127 151
126 3528 3515 2733 331 328 692
127 105 119 95 48 49 39
128 1097 1712 1079 243 265 183
129 734 571 528 165 92 71
130 396 81 30 246 316 246
131 5314 5481 6963 1103 1624 1571
132 1250 1297 1350 254 300 295
133 14 273 95 37 28 35
134 708 730 865 154 267 166
135 2527 2266 2502 327 186 201
136 278 199 238 87 94 49
137 236 153 274 17 24 35
138 21 88 154 15 83 18
139 437 143 263 52 63 44
140 349 449 372 86 135 97
141 1134 1061 948 231 310 240
142 228 108 40 49 9 8
143 33 64 24 14 13 19
144 19 20 16 14 7 10
145 41 114 81 18 16 21
146 491 425 483 87 134 87
147 2862 7 7191 1853 5 1507
148 10375 4901 27761 1922 3855 1029
149 59 60 81 14 67 26
150 405 606 678 81 373 210
151 902 1614 1147 220 370 386
152 1113 307 734 322 275 1479
153 1133 806 1553 672 916 569
154 27 24 28 22 11 31
155 578 596 218 232 150 127
156 441 448 474 53 61 31
157 163 90 222 52 40 41
158 358 336 277 85 59 51
159 855 384 475 50 46 36
160 53 81 94 29 26 23
161 247 354 341 113 119 64
162 46 612 1018 439 184 458
163 11399 14987 7569 624 537 1077
164 30 52 45 36 23 14
165 721 616 703 78 64 103
166 462 1873 2797 320 383 241
167 14 17 10 8 15 26
168 724 776 730 112 168 120
169 46 158 63 28 35 27
170 103 95 78 18 38 19
171 1675 214 301 68 99 836
172 292 676 290 35 97 69
173 210 179 122 41 80 78
174 1111 802 1017 232 185 248
175 48 121 197 24 34 26
176 5387 7254 2081 773 1784 897
177 1744 1202 258 34 263 248
178 420 294 477 65 48 55
179 84 76 150 27 97 27
180 273 385 309 67 302 90
181 19 475 139 27 428 102
182 273 1681 976 190 1341 415
183 1310 1246 1476 296 293 244
184 43 14 11 9 5 3
185 71 77 74 12 26 15
186 1445 1817 1500 416 433 317
187 123 242 125 34 37 17
188 2058 1996 2131 380 297 287
189 880 603 650 184 195 182
190 145 262 243 52 59 77
191 1862 1247 1061 89 398 231
192 1254 1533 1589 358 287 299
193 997 658 840 152 146 153
194 31 115 318 12 13 18
195 1455 3175 3176 196 465 263
196 625 327 362 88 67 26
197 5385 15560 12075 3021 1032 1817
198 39 161 93 41 15 46
199 13 26 11 16 7 12
200 1886 1515 2128 375 261 240
201 62 171 175 23 66 32
202 49 82 106 25 106 29
203 259 393 355 134 114 59
204 185 364 373 62 99 91
205 30 60 53 9 19 16
206 540 373 453 297 31 51
207 699 726 1046 233 321 263
208 16 19 12 6 10 7
209 702 757 1050 112 336 327
210 403 652 654 242 567 271
211 1609 1340 1532 477 592 283
212 480 1210 735 66 57 75
213 142 1067 439 59 52 37
214 85 135 131 23 34 23
215 5182 1560 5154 802 3620 809
216 22 55 48 11 64 26
217 107 396 1235 46 1304 93
218 38 52 90 11 43 24
219 306 631 426 38 32 24
220 179 281 535 29 130 29
221 150 378 729 117 157 94
222 39 30 8 15 5 17
223 363 538 577 132 120 109
224 128 527 187 49 24 27
225 132 77 146 25 18 11
226 212 196 301 168 138 156
227 45 161 90 10 23 11
228 235 125 154 23 83 52
229 205 171 164 53 11 22
230 1067 1169 595 346 222 255
231 79 511 262 48 62 72
232 106 125 150 23 100 27
233 1202 1009 1081 239 193 250
234 1028 533 370 196 204 179
235 73 196 17 12 61 22
236 230 322 439 95 172 117
237 21 20 28 8 262 9
238 137 87 63 28 107 53
239 4875 2120 2463 571 279 379
240 489 223 201 74 99 96
241 74 64 81 35 21 13
242 10 37 10 19 15 18
243 22 920 72 1070 92 3
244 596 124 899 254 34 30
245 161 233 174 22 25 15
246 797 179 431 60 52 102
247 18 19 27 18 13 7
248 1226 1453 1713 149 43 72
249 26 30 12 10 12 12
250 185 430 151 48 103 52
251 810 2838 3873 757 539 337
252 321 253 420 131 165 107
253 153 235 355 54 362 36
254 322 708 910 143 317 202
255 2305 2564 7421 2880 2838 1142
256 2735 2489 2454 525 550 985
257 137 103 61 165 155 142
258 1171 680 1026 142 103 143
259 15 14 14 12 8 7
260 13 18 7 11 8 12
261 616 515 374 112 62 55
262 77 81 133 46 72 42
263 390 220 396 61 95 88
264 26 31 130 16 12 8
265 166 243 186 146 101 108
266 86 90 50 67 62 80
267 16 33 13 45 44 36
268 26 39 42 27 48 46
269 126 196 278 96 213 121
270 1142 2239 1310 163 133 175
271 87 226 190 84 136 66
272 188 166 111 94 80 86
273 39 50 116 28 118 40
274 283 311 502 128 284 135
275 126 262 220 50 56 47
276 249 176 844 194 71 81
277 55 96 119 42 154 60
278 430 2283 912 242 285 252
279 289 576 665 204 145 124
280 693 724 410 123 127 140
281 840 5543 3269 1087 465 727
282 87 144 244 66 239 88
283 1223 1773 2169 307 446 219
284 978 690 1096 319 531 817
285 586 179 62 29 29 21
286 524 481 528 136 147 143
287 3795 3477 4876 1137 1313 1528
288 42 80 122 42 37 34
289 60 157 147 53 77 68
290 1563 49 13 85 19 43
291 166 1693 910 698 482 352
292 498 273 387 182 64 162
293 29 53 48 13 28 18
294 34 98 69 37 28 50
295 1262 892 765 206 278 191
296 23 59 49 26 22 27
297 886 850 442 118 54 119
298 4277 17657 4159 1212 332 377
299 2955 457 326 194 26 25
300 602 112 92 70 31 55
301 122 301 288 34 85 74
302 8 19 30 17 40 11
303 2172 2643 1762 389 511 453
304 497 275 277 52 52 39
305 1218 141 707 486 99 107
306 720 590 684 168 198 247
307 24913 25552 24990 3683 11795 5834
308 892 822 730 162 200 164
309 49 56 29 18 23 15
310 1561 1594 3080 547 4676 900
311 33 31 29 18 9 14
312 8 27 12 5 5 4
313 163 243 72 34 58 15
314 59 137 249 19 320 19
315 568 576 1239 151 121 71
316 2083 1589 1876 325 1273 799
317 462 3394 853 358 121 121
318 1623 6098 3180 1567 85 731
319 1069 168 72 94 37 58
320 132 144 201 36 60 83
321 69 28 9 13 13 14
322 183 162 177 55 88 51
323 17 59 46 7 23 7
324 59 87 113 31 175 28
325 553 175 78 56 20 17
326 968 1685 1381 128 248 299
327 173 309 858 221 403 119
328 331 214 191 34 29 51
329 1290 706 2169 328 349 522
330 3336 14237 6907 659 690 1234
331 709 910 1428 462 884 455
332 1256 710 323 124 115 125
333 61 162 104 22 26 23
334 44 33 18 20 16 27
335 309 658 371 239 137 174
336 174 303 365 62 107 73
337 395 862 111 174 44 30
338 4106 2986 4471 1196 1013 909
339 411 580 935 284 758 240
340 305 424 447 94 167 73
341 190 487 298 42 149 92
342 5618 3097 2605 752 714 553
343 2136 2282 3342 303 374 475
344 3679 1118 1834 547 561 1424
345 988 712 813 394 268 472
346 140 195 351 40 106 29
347 127 605 301 250 54 131
348 23 23 26 10 30 16
349 1175 788 1202 140 104 173
350 1590 644 56 217 48 69
351 1170 1367 1087 240 188 104
352 167 325 579 121 185 77
353 19 28 14 7 9 10
354 16503 4973 6063 1842 3129 2001
355 19 37 32 22 35 15
356 257 978 431 59 103 80
357 2178 1082 1461 760 505 545
358 90 1514 584 210 168 174
359 256 113 46 42 19 15
360 32 16 13 17 14 16
361 2183 41 15 46 16 14
362 4093 604 598 173 111 127
363 179 121 159 71 88 43
364 353 1164 486 75 112 111
365 78 101 113 17 18 18
366 287 575 978 89 32 36
367 91 834 176 23 67 34
368 906 881 1102 138 145 166
369 382 1005 506 50 76 102
370 4991 5671 3489 697 728 699
371 215 585 578 149 249 185
372 1431 1758 1176 271 511 379
373 528 404 575 185 189 318
374 14 24 18 17 15 16
375 48 151 83 16 117 28
376 2402 7712 4077 407 1377 1068
377 139 124 226 54 68 49
378 904 1055 692 297 394 342
379 496 357 280 109 72 141
380 977 3022 1572 516 319 367
381 526 1142 793 223 557 319
382 1701 2771 2433 578 557 481
383 130 184 296 31 90 34
384 146 107 35 29 69 40
385 120 448 607 192 77 134
386 58 87 147 21 43 15
387 15117 13803 10570 1390 2879 1351
388 570 131 291 41 59 25
389 1024 1289 1253 265 392 390
390 38 50 64 24 86 11
391 57 72 45 16 35 22
392 9 14 11 11 13 10
393 592 453 492 181 230 189
394 99 88 108 43 69 49
395 314 473 623 99 200 62
396 1191 736 1092 135 186 277
397 85 132 136 18 21 23
398 11 22 13 20 9 10
399 829 5853 1887 437 1530 273
400 207 336 451 131 156 107
401 290 132 281 96 70 37
402 107 321 162 25 40 42
403 16 95 22 23 34 8
404 637 705 660 153 145 145
405 131 137 81 26 31 25
406 5458 12843 7022 929 1253 911
407 762 746 900 255 406 511
408 33 46 28 23 15 23
409 6373 330 190 20 463 39
410 14 15 10 8 10 6
411 3846 5813 12715 1867 1853 1187
412 1890 995 534 92 71 62
413 463 428 947 212 269 196
414 26 31 47 12 21 17
415 16 118 61 39 17 16
416 480 433 500 253 199 236
417 2583 2351 3101 620 756 524
418 301 421 705 65 444 91
419 248 320 714 76 246 48
420 115 65 47 21 29 41
421 53 113 168 33 159 36
422 273 24 855 171 124 18
423 86 481 239 25 47 33
424 17 20 15 19 49 12
425 137 112 126 39 25 30
426 170 388 253 52 92 45
427 92 225 219 34 34 23
428 658 746 1094 106 128 139
429 1202 783 1165 165 239 583
430 31 54 50 17 73 30
431 228 277 515 89 458 145
432 298 241 285 67 69 58
433 59 37 22 65 16 12
434 885 626 988 93 93 81
435 264 157 212 66 48 38
436 222 211 219 50 40 93
437 1137 1405 2983 667 1068 582
438 7367 144 191 165 39 46
439 30 28 21 20 21 22
440 1273 664 932 304 448 289
441 540 329 486 123 119 156
442 741 955 1459 744 846 707
443 1472 54 79 67 31 83
444 632 147 178 93 40 190
445 117 212 91 31 30 45
446 460 897 1526 295 216 116
447 48 158 57 33 32 35
448 32 32 9 15 10 11
449 107 268 423 118 128 120
450 2127 2109 1160 489 504 434
451 14 14 14 15 15 19
452 382 273 242 71 85 75
453 355 517 138 67 155 42
454 764 703 725 219 510 348
455 1247 1620 999 586 836 295
456 1269 1261 1287 149 138 111
457 19 30 57 20 30 18
458 171 277 217 35 53 48
459 327 342 254 45 72 80
460 1581 3640 1674 513 358 126
461 13281 8295 11514 1698 2312 1657
462 127 126 104 44 46 25
463 727 545 542 250 200 111
464 24 55 42 14 23 16
465 92 64 25 29 23 28
466 902 1184 1370 183 255 213
467 19 20 5 13 13 14
468 554 364 153 160 182 40
469 392 260 344 68 70 88
470 27 40 46 16 21 10
471 1441 291 312 64 44 38
472 1541 482 920 136 111 101
473 14 9 5 15 2 16
474 25 21 19 24 19 19
475 382 249 355 83 109 67
476 634 578 1175 258 729 202
477 779 733 1050 244 192 232
478 4005 2944 3818 723 585 670
479 484 644 764 100 176 107
480 20 15 12 12 18 18
481 274 312 334 92 164 88
482 147 80 97 43 27 55
483 23 27 13 17 30 22
484 129 178 104 73 53 69
485 12692 8136 8567 2889 2092 2286
486 4075 1689 2716 555 423 394
487 909 1193 2124 171 132 127
488 615 89 62 33 40 66
489 550 678 1111 237 194 301
490 950 163 116 225 19 277
491 117 118 15 26 23 75
492 193 112 113 54 30 104
493 51 22 16 25 17 23
494 28 34 61 27 180 11
495 44 33 142 20 16 22
496 492 261 426 136 65 81
497 375 654 540 158 559 499
498 31 139 74 149 17 74
499 97 153 204 42 40 39
500 812 183 157 25 53 27
501 33 54 83 12 19 29
502 429 350 413 85 75 55
503 223 607 343 154 135 110
504 51 25 29 14 24 22
505 2032 1572 1467 477 235 232
506 55 14 18 22 12 22
507 92 172 120 15 13 27
508 123 326 234 46 72 34
509 111 215 275 42 76 25
510 155 115 171 38 29 33
511 583 442 448 189 113 895
512 28 59 53 16 171 7
513 1092 1228 2376 303 527 401
514 904 734 1154 338 273 309
515 432 351 406 78 61 45
516 405 530 478 61 60 72
517 2568 1689 2081 879 594 551
518 192 224 305 52 197 70
519 120 91 68 31 228 30
520 908 891 1056 306 198 270
521 47 120 58 11 27 9
522 53 66 50 31 31 20
523 441 1859 1846 381 351 318
524 3352 4220 4271 596 2080 895
525 1447 2863 2801 960 3944 1218
526 348 248 382 128 850 187
527 2623 3344 3345 1271 873 2022
528 114 99 53 29 30 43
529 114 113 144 28 21 40
530 45 530 76 41 38 42
531 403 423 422 140 88 92
532 272 408 481 94 109 79
533 756 607 976 292 275 173
534 193 157 278 52 78 36
535 1154 177 140 57 47 26
536 2252 715 951 233 153 253
537 2330 1311 2143 222 203 247
538 343 504 485 154 93 119
539 300 896 525 66 110 412
540 3181 3354 1977 571 309 387
541 607 3706 509 563 87 60
542 15993 15141 36135 6166 9687 3755
543 486 474 416 138 172 299
544 155 247 298 80 158 81
545 765 401 591 52 52 111
546 8733 8615 6035 1913 1167 1422
547 67 53 76 28 86 37
548 66 132 307 26 38 23
549 693 1752 743 107 60 215
550 102 389 146 33 41 38
551 16936 9301 12551 3335 3322 2815
552 86 81 86 54 28 24
553 1127 672 719 287 450 448
554 3664 12227 20241 2236 975 791
555 6 12 16 20 22 14
556 2421 243 435 161 247 542
557 309 1093 667 95 118 70
558 3581 3903 3599 819 874 752
559 601 483 811 158 112 98
560 1391 1165 1136 316 548 435
561 317 648 645 150 189 168
562 89 44 15 32 26 20
563 109 133 167 53 44 54
564 647 344 213 61 82 73
565 20 47 3 28 20 26
566 305 263 473 53 72 58
567 931 1088 854 352 454 269
568 468 424 600 108 196 196
569 311 376 531 124 276 113
570 116 163 262 72 252 55
571 22 76 151 30 116 25
572 692 717 602 105 77 51
573 456 644 380 175 298 158
574 1159 85 59 102 59 67
575 17 22 8 29 15 27
576 2964 5178 3311 421 638 647
577 1022 897 714 345 410 328
578 353 229 172 40 24 26
579 209 315 361 124 101 78
580 125 317 208 54 46 187
581 3720 2923 3282 182 863 754
582 711 658 729 234 226 228
583 1403 740 589 164 241 486
584 93 79 123 35 76 30
585 47 35 112 28 33 49
586 42 30 90 38 61 50
587 22 13 15 29 28 21
588 7733 8486 6465 276 1355 3140
589 2566 1989 1539 343 267 65
590 20 20 24 17 25 26
591 110 345 181 41 52 24
592 82 241 283 40 130 72
593 37 78 99 34 46 39
594 31 37 42 34 36 22
595 187 40 164 60 22 31
596 58 32 9 17 17 8
597 81 36 62 36 28 37
598 22 54 34 13 35 44
599 1023 166 294 51 44 101
600 77 53 13 26 22 24
601 124 51 33 35 21 28
602 17 63 14 16 16 25
603 2565 808 601 272 315 262
604 330 461 106 67 37 38
605 17 21 33 25 60 23
606 249 80 22 80 70 180
607 186 100 137 28 28 31
608 2538 812 2325 106 317 61
609 148 151 216 51 57 29
610 60 42 8 32 21 44
611 68 122 248 46 76 31
612 462 729 331 80 289 605
613 73 45 45 22 28 29
614 376 374 157 66 59 67
615 320 96 102 97 201 201
616 252 179 153 33 41 40
617 114 556 408 113 383 137
618 80 91 264 54 68 25
619 860 749 788 115 255 173
620 17 52 84 25 78 22
621 692 776 728 142 95 85
622 2987 4922 4443 953 602 1085
623 1553 1391 1267 306 269 215
624 49 85 101 30 42 35
625 246 123 314 248 88 58
626 176 283 245 48 91 56
627 41 6891 3184 1455 513 1000
628 231 117 123 38 68 60
629 103 214 174 47 673 37
630 332 221 354 209 135 150
631 231 857 511 138 394 255
632 6150 4264 7607 575 1252 644
633 307 305 265 85 133 113
634 296 487 439 43 40 70
635 196 144 193 71 53 30
636 113 32 35 34 26 22
637 118 40 42 30 32 29
638 163 196 163 36 52 67
639 82 130 217 29 22 21
640 670 680 844 195 399 157
641 597 593 896 116 81 108
642 6505 6785 16375 5762 10826 4397
643 57 68 46 29 18 20
644 368 214 407 102 177 95
645 66 284 94 29 53 26
646 39 30 27 18 22 25
647 1034 869 289 128 40 65
648 163 208 231 60 53 47
649 812 317 639 138 80 78
650 50 46 27 23 137 21
651 818 1268 996 159 214 254
652 83 344 194 94 96 98
653 56 198 219 45 39 33
654 1642 2311 2848 575 1721 1326
655 419 25 19 21 19 27
656 63 18 19 33 17 23
657 385 156 131 101 56 61
658 59 755 664 203 178 252
659 143 179 153 49 70 47
660 70 34 44 61 27 24
661 15 14 18 21 25 32
662 174 176 216 77 143 65
663 26 157 44 29 63 45
664 613 177 421 215 127 155
665 666 490 593 140 205 95
666 106 146 206 63 149 65
667 451 1340 766 108 223 195
668 156 58 110 23 79 117
669 1726 829 2747 196 265 237
670 2857 3464 1718 343 379 303
671 100 99 47 29 89 27
672 165 244 380 40 109 72
673 642 759 1607 100 91 95
674 16 38 48 17 38 17
675 148 189 194 71 45 43
676 97 138 51 35 14 25
677 141 74 35 26 18 15
678 199 40 8 15 19 13
679 732 760 732 305 285 313
680 134 84 228 34 197 26
681 565 1442 974 477 182 327
682 2622 549 605 187 114 160
683 8474 133 222 226 225 95
684 119 200 146 30 27 21
685 29639 22468 24741 3051 6006 3822
686 625 713 324 136 286 131
687 3055 2714 7874 2692 4927 2049
688 105 112 248 72 93 50
689 430 525 545 185 287 109
690 1465 845 1719 487 620 449
691 1017 838 1179 126 412 230
692 799 779 533 162 165 129
693 36 35 434 40 42 37
694 289 432 201 83 95 92
695 575 162 139 87 53 120
696 620 532 627 165 143 87
697 142 111 153 40 54 28
698 137 88 380 41 80 33
699 26 15 25 30 23 35
700 90 112 180 33 70 25
701 46 32 21 23 20 49
702 2933 1219 2159 524 377 464
703 8845 2938 4519 1029 655 855
704 51 55 89 38 37 28
705 406 169 310 96 70 89
706 1092 1135 1248 160 148 136
707 32 55 113 28 39 23
708 68 25 49 41 15 19
709 45 61 40 39 35 29
710 44 69 17 26 19 21
711 288 1846 416 245 961 111
712 37 72 101 35 75 47
713 55 108 204 54 104 35
714 269 176 305 106 51 89
715 147 175 165 40 35 33
716 2215 1690 1767 452 455 404
717 2467 967 1219 290 414 254
718 44 47 59 28 68 28
719 752 1675 1344 452 380 240
720 412 634 342 83 99 84
721 1221 571 997 227 392 488
722 1882 448 855 187 397 497
723 28 29 42 41 31 24
724 163 255 185 51 52 30
725 4401 151 18 321 31 47
726 65 43 60 30 44 26
727 979 658 591 141 196 153
728 585 127 164 82 51 42
729 630 445 451 185 172 164
730 2224 1065 1124 345 293 373
731 2273 701 332 1702 276 87
732 1200 830 814 266 252 227
733 240 371 506 93 127 97
734 131 257 88 61 124 78
735 204 298 608 98 65 46
736 1374 2706 1901 869 436 381
737 616 246 177 82 96 117
738 129 72 16 47 40 38
739 1463 956 1387 369 280 200
740 92 157 258 57 154 50
741 128 83 64 72 50 63
742 220 413 598 199 452 364
743 1238 1228 1248 330 290 262
744 297 67 76 63 50 44
745 240 102 28 89 54 57
746 72 76 21 41 38 41
747 43 79 50 42 75 61
748 119 106 120 27 51 47
749 364 344 685 125 126 129
750 302 73 339 82 107 74
751 2453 2224 1729 4504 3552 4425
752 27681 23254 17945 42598 31296 38967
753 46 66 50 88 57 84
754 470 503 338 925 602 845
755 10228 8647 6685 16351 13062 16298
756 103 88 70 169 139 189
757 13 22 11 20 26 31
758 17 14 15 18 21 16
759 16 26 14 20 27 22
760 12 12 7 20 12 17
761 11 21 17 14 19 9
762 7 13 5 14 13 17
763 19 17 17 38 29 26
764 10 18 12 35 32 33
765 13464 15704 9279 3538 5928 3098
766 3278 1478 2483 658 451 533
767 561 533 515 130 135 517
768 1057 972 1130 110 112 143
769 1616 1190 1164 260 227 327
770 3813 2452 2351 570 342 449
771 2417 2032 2642 467 286 425
772 470 359 633 80 79 120
773 589 369 587 171 159 134
774 737 411 541 211 195 117
775 7198 8339 7887 1315 2365 1823
776 578 594 503 111 54 115
777 979 638 1180 146 224 149
778 1253 1265 1665 140 205 205
779 971 389 707 248 207 184
780 901 870 976 163 187 162
781 628 527 633 125 55 88
782 771 675 645 211 200 169
783 336 342 317 61 48 87
784 1321 1163 1321 449 423 578
pre_count_5 post_count_5
1 20 15
2 147 125
3 53 13
4 73 103
5 1997 4576
6 207 132
7 550 379
8 57 56
9 1662 1172
10 297 144
11 11 56
12 10 15
13 21 30
14 267 274
15 938 821
16 45 38
17 333 622
18 31 23
19 31 25
20 51 71
21 12 18
22 20 37
23 150 155
24 334 402
25 80 66
26 36 29
27 562 904
28 80 92
29 312 204
30 16 23
31 99 67
32 28 24
33 299 668
34 554 594
35 1440 2616
36 2091 6004
37 80 73
38 222 235
39 5099 4202
40 790 546
41 82 87
42 174 122
43 1686 613
44 111 153
45 96 125
46 157 139
47 177 100
48 31 28
49 50 57
50 143 112
51 232 243
52 11 16
53 396 421
54 12 66
55 88 48
56 9 17
57 18 21
58 22 19
59 400 476
60 34 30
61 25 34
62 283 375
63 93 112
64 169 182
65 26 32
66 357 547
67 75 55
68 159 72
69 43 52
70 22 25
71 65 70
72 44 62
73 18 9
74 36 41
75 18 25
76 91 77
77 37 46
78 38 38
79 113 78
80 533 447
81 108 96
82 671 344
83 20 38
84 24 12
85 341 257
86 184 157
87 25 20
88 233 326
89 13 637
90 684 643
91 42 37
92 334 15
93 228 173
94 50 64
95 299 238
96 73 108
97 15 15
98 83 68
99 13 14
100 17 28
101 59 38
102 95 87
103 696 430
104 204 188
105 39 26
106 1116 1037
107 360 225
108 332 242
109 271 239
110 49 20
111 18 17
112 26 47
113 166 253
114 31 70
115 149 113
116 82 306
117 31 45
118 869 375
119 13 6
120 109 241
121 21 33
122 92 107
123 141 187
124 174 284
125 58 108
126 1137 492
127 38 106
128 238 375
129 162 161
130 167 46
131 1623 1896
132 290 481
133 118 73
134 201 250
135 232 320
136 109 159
137 60 30
138 42 24
139 59 48
140 123 188
141 242 320
142 16 17
143 20 27
144 7 9
145 11 18
146 103 105
147 13 6
148 1633 1587
149 39 26
150 151 173
151 306 377
152 317 245
153 430 624
154 26 23
155 156 177
156 41 60
157 61 63
158 54 127
159 90 92
160 18 19
161 79 94
162 205 208
163 3674 2681
164 23 29
165 83 110
166 851 897
167 14 10
168 186 181
169 46 79
170 22 21
171 93 169
172 44 85
173 71 95
174 260 345
175 29 22
176 1612 803
177 227 937
178 44 51
179 39 47
180 91 140
181 76 124
182 245 621
183 357 345
184 8 6
185 19 25
186 637 733
187 39 50
188 493 531
189 274 225
190 34 120
191 623 134
192 396 698
193 179 223
194 14 25
195 264 815
196 80 76
197 3261 6280
198 28 46
199 17 8
200 379 365
201 42 47
202 43 43
203 67 137
204 68 89
205 12 13
206 43 84
207 219 297
208 6 11
209 452 343
210 309 437
211 546 829
212 206 234
213 90 127
214 32 20
215 475 961
216 24 20
217 135 82
218 32 21
219 46 241
220 55 32
221 79 107
222 22 18
223 92 151
224 29 45
225 18 25
226 98 155
227 18 17
228 60 45
229 51 29
230 662 622
231 70 118
232 33 53
233 210 379
234 184 162
235 40 17
236 121 123
237 51 29
238 47 44
239 427 756
240 191 167
241 32 23
242 20 20
243 797 1181
244 64 42
245 45 26
246 115 63
247 16 9
248 73 347
249 21 10
250 109 100
251 1984 896
252 68 130
253 134 92
254 171 257
255 1211 1833
256 1228 886
257 152 146
258 149 144
259 7 13
260 7 5
261 55 63
262 58 44
263 74 68
264 20 7
265 107 153
266 58 79
267 49 40
268 42 35
269 124 120
270 205 347
271 73 115
272 110 119
273 60 55
274 167 127
275 57 76
276 90 88
277 70 53
278 230 872
279 127 171
280 216 127
281 635 2215
282 115 84
283 1178 684
284 548 484
285 138 86
286 239 136
287 1245 1529
288 82 32
289 60 62
290 77 38
291 429 1482
292 108 134
293 20 21
294 34 50
295 385 469
296 51 21
297 178 114
298 914 2329
299 177 102
300 140 93
301 48 73
302 21 17
303 687 1039
304 71 83
305 214 96
306 158 235
307 5651 8227
308 224 259
309 20 17
310 1866 771
311 39 15
312 14 7
313 24 50
314 77 29
315 154 133
316 877 720
317 172 664
318 1148 1236
319 112 86
320 35 62
321 17 15
322 61 54
323 22 11
324 42 33
325 60 38
326 238 428
327 11 128
328 46 53
329 353 314
330 2349 2884
331 458 566
332 203 192
333 29 24
334 17 23
335 252 404
336 51 89
337 231 183
338 1018 1339
339 274 292
340 112 165
341 133 68
342 976 370
343 531 526
344 576 388
345 404 399
346 62 47
347 135 381
348 20 11
349 173 135
350 1678 450
351 184 262
352 117 149
353 10 12
354 4351 2747
355 24 19
356 168 121
357 554 538
358 109 464
359 19 24
360 16 8
361 54 36
362 253 236
363 96 71
364 87 327
365 15 22
366 208 153
367 102 94
368 269 207
369 632 482
370 1090 960
371 141 248
372 801 640
373 218 248
374 19 14
375 34 44
376 1034 2491
377 61 55
378 402 493
379 107 154
380 502 1285
381 248 375
382 600 953
383 56 61
384 80 77
385 131 233
386 39 21
387 4509 4491
388 44 45
389 746 462
390 16 47
391 16 31
392 9 11
393 222 255
394 42 27
395 129 176
396 194 215
397 33 29
398 11 17
399 734 1180
400 112 215
401 56 52
402 54 36
403 17 45
404 143 187
405 57 30
406 1325 1606
407 375 329
408 12 28
409 201 25
410 6 10
411 765 1407
412 160 135
413 193 210
414 16 21
415 33 61
416 171 224
417 786 735
418 147 124
419 75 72
420 58 44
421 68 47
422 119 50
423 33 53
424 13 14
425 30 39
426 64 79
427 40 38
428 144 150
429 482 304
430 40 33
431 166 120
432 105 93
433 20 23
434 109 108
435 72 52
436 101 50
437 579 706
438 307 182
439 22 32
440 431 396
441 162 126
442 423 535
443 104 66
444 546 89
445 78 48
446 256 289
447 82 47
448 13 26
449 69 121
450 454 559
451 22 23
452 137 102
453 90 76
454 334 286
455 1178 814
456 172 196
457 22 14
458 38 33
459 137 109
460 221 523
461 2557 1484
462 54 65
463 227 287
464 8 19
465 42 38
466 314 275
467 10 8
468 139 292
469 65 92
470 15 16
471 45 85
472 131 94
473 7 15
474 20 17
475 97 98
476 283 243
477 195 228
478 758 582
479 176 181
480 11 22
481 184 88
482 32 32
483 11 18
484 80 82
485 2733 3255
486 468 589
487 156 135
488 111 60
489 207 349
490 165 46
491 33 31
492 83 47
493 17 26
494 53 34
495 15 44
496 123 70
497 251 326
498 34 80
499 31 37
500 220 28
501 13 24
502 61 109
503 86 341
504 19 16
505 405 516
506 28 12
507 37 33
508 39 65
509 65 38
510 35 30
511 787 166
512 60 19
513 533 569
514 287 249
515 53 109
516 167 110
517 426 850
518 60 91
519 61 46
520 452 440
521 35 16
522 51 39
523 107 729
524 1264 1251
525 2075 1687
526 201 142
527 979 1529
528 40 76
529 51 37
530 51 57
531 115 101
532 83 94
533 211 280
534 58 37
535 66 38
536 247 299
537 276 225
538 103 194
539 541 129
540 695 865
541 132 488
542 4256 5368
543 137 157
544 86 96
545 83 68
546 2512 2884
547 51 29
548 41 36
549 469 446
550 46 40
551 3960 3545
552 53 28
553 465 487
554 2513 2526
555 18 19
556 500 357
557 204 227
558 1076 1316
559 132 109
560 571 663
561 222 339
562 33 36
563 53 69
564 149 127
565 21 22
566 46 58
567 396 418
568 244 216
569 130 134
570 67 70
571 43 24
572 62 79
573 234 251
574 181 87
575 23 13
576 445 932
577 392 579
578 39 51
579 144 179
580 189 95
581 1100 651
582 220 326
583 291 228
584 31 50
585 32 60
586 37 28
587 24 18
588 4475 3540
589 449 404
590 37 16
591 103 70
592 45 66
593 40 53
594 28 34
595 45 29
596 21 17
597 31 34
598 27 32
599 118 103
600 20 28
601 55 25
602 19 17
603 696 393
604 41 134
605 29 20
606 48 28
607 18 22
608 382 91
609 41 35
610 25 18
611 46 35
612 197 169
613 22 19
614 119 109
615 145 87
616 95 81
617 130 259
618 38 55
619 196 156
620 29 24
621 112 120
622 791 1088
623 294 326
624 40 67
625 141 139
626 64 84
627 362 3524
628 63 50
629 212 72
630 167 187
631 173 313
632 670 731
633 150 169
634 61 94
635 57 74
636 26 45
637 30 22
638 59 44
639 40 32
640 365 280
641 126 101
642 4299 5723
643 38 26
644 109 134
645 40 64
646 30 22
647 84 119
648 52 62
649 99 88
650 62 16
651 455 297
652 84 135
653 42 89
654 664 967
655 17 33
656 22 19
657 72 121
658 43 358
659 59 57
660 19 30
661 32 32
662 78 115
663 86 54
664 179 128
665 212 92
666 89 63
667 374 227
668 301 111
669 168 246
670 1134 605
671 24 94
672 45 59
673 106 79
674 12 21
675 48 75
676 22 20
677 25 24
678 13 20
679 622 447
680 41 31
681 339 741
682 207 130
683 186 127
684 51 36
685 4081 3240
686 287 372
687 2321 2541
688 55 66
689 181 138
690 624 534
691 161 195
692 212 216
693 34 50
694 110 136
695 82 83
696 111 133
697 70 53
698 50 47
699 35 21
700 43 40
701 16 30
702 486 463
703 1153 1248
704 34 40
705 95 92
706 154 183
707 25 18
708 53 34
709 29 32
710 25 31
711 338 782
712 41 25
713 45 37
714 82 78
715 40 48
716 591 581
717 373 337
718 42 27
719 409 501
720 365 122
721 279 285
722 302 279
723 33 26
724 48 60
725 367 117
726 31 34
727 231 212
728 66 68
729 163 280
730 386 392
731 225 188
732 370 351
733 103 125
734 52 122
735 62 68
736 375 2032
737 173 97
738 31 43
739 348 477
740 92 64
741 75 52
742 237 342
743 392 416
744 69 46
745 63 69
746 54 45
747 58 57
748 45 38
749 128 218
750 64 63
751 4346 4501
752 37992 40969
753 93 82
754 820 864
755 15828 16719
756 169 167
757 24 31
758 22 18
759 24 16
760 12 19
761 16 15
762 14 14
763 41 36
764 21 32
765 7791 4718
766 667 653
767 486 151
768 191 153
769 267 313
770 596 572
771 365 481
772 120 95
773 237 220
774 321 254
775 1643 2122
776 97 98
777 166 177
778 374 216
779 258 184
780 289 194
781 81 121
782 290 280
783 83 71
784 547 586Augmentation of the data
# Creating wide data frame
df_clean <- read.csv(here("data/02_dat_clean.csv"))
df_wide <- df_clean |>
# replace outliers for pre and post_count columns
replace_outliers_with_na("pre_count") |>
replace_outliers_with_na("post_count") |>
rowwise() |>
# calculate means
mutate(mean_pre =
round(mean(c_across(starts_with("pre_count")), na.rm = TRUE), 1),
mean_post =
round(mean(c_across(starts_with("post_count")), na.rm = TRUE), 1)) |>
ungroup() |>
# fold change made of case/control
mutate(log2_fold_change = log2(mean_post / mean_pre))
# save data
write_csv(df_wide, here("data/03_dat_aug_01.csv"))
# make a longer data frame with a row for each "count" variable
df_long <- df_wide |>
pivot_longer(
cols = starts_with("pre_count") | starts_with("post_count"), # select count columns
names_to = "treatment", # new column for column names
values_to = "count_value" # new column for values
) |>
mutate(log2_count_value = log2(count_value)) |> # calculate log2 of counts
mutate(bin_treatment = case_when(
str_detect(treatment, "^pre") ~ 0, # change "pre" to 0
str_detect(treatment, "^post") ~ 1)) |> # change "post" to 1
mutate(treatment = case_when(
str_detect(treatment, "^pre") ~ "pre", # change to "pre"
str_detect(treatment, "^post") ~ "post"))
# save data
write_csv(df_long, here("data/03_dat_aug_02.csv"))Descriptive statistics
Distribution of log2 fold change per class
Are there significance in the log2 fold change for some genes?
- Nest data
- Fitting linear models
- Tidying linear model results with confidence intervals
- Unnesting
- Filtering and selecting treatment effects from linear model estimates
Results
Most up and downregulated genes with the treatment
Discussion and conclusion
- Were any genes significantly up or downregulated with this treatment?
- What effect could removing outliers have on the findings?
- How could the analysis be improved?